Collaboration, Out-Licensing and Related Agreements - Additional Information (Detail) $ in Thousands, € in Millions |
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1 Months Ended |
3 Months Ended |
6 Months Ended |
12 Months Ended |
25 Months Ended |
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Nov. 09, 2024 |
Feb. 22, 2023
USD ($)
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Feb. 22, 2023
EUR (€)
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Jun. 30, 2025
USD ($)
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Jun. 30, 2025
EUR (€)
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May 31, 2025
Doctor
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Nov. 30, 2024
USD ($)
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Aug. 31, 2024
USD ($)
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Jun. 30, 2024
USD ($)
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Jun. 30, 2024
EUR (€)
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May 31, 2024
USD ($)
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Mar. 31, 2024
USD ($)
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Mar. 31, 2021
USD ($)
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Nov. 30, 2020
USD ($)
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Sep. 30, 2020
USD ($)
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Sep. 30, 2020
EUR (€)
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Jul. 31, 2020
USD ($)
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Mar. 31, 2020
USD ($)
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Jun. 30, 2025
USD ($)
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Jun. 30, 2024
USD ($)
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Jun. 30, 2025
USD ($)
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Jun. 30, 2024
USD ($)
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Dec. 31, 2021
USD ($)
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Dec. 31, 2020
USD ($)
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Mar. 31, 2025
USD ($)
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Dec. 31, 2024
USD ($)
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Selling, general and administrative expenses related party amount |
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$ 54,312
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$ 8,944
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$ 95,416
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$ 16,902
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Other accrued liabilities |
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$ 1,418
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1,418
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1,418
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$ 0
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Financing liability |
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71,959
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71,959
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71,959
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69,383
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Revenue under collaboration agreements |
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15,717
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500
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23,690
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500
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Contract liability, current |
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746
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746
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746
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557
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Contract liability, noncurrent |
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1,103
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1,103
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1,103
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1,532
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EEA License [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Performance obligation, transaction price |
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69,400
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69,400
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69,400
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Financing liability |
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$ 69,400
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ROW License [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Performance obligation, transaction price |
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73,100
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73,100
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73,100
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Revenue under collaboration agreements |
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73,100
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Development and Regulatory Services [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Performance obligation, transaction price |
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2,600
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2,600
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2,600
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Alfresa Agreement [Member] | License Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 2,000
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Milestone Payments |
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13,000
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13,000
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Initial Transaction Price |
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7,000
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Contract with Customer, Liability, Revenue Recognized |
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0
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$ 0
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0
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$ 0
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Contract with Customer, Liability |
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0
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0
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0
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0
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Milestone payments earned |
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11,000
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Remaining regulatory milestone |
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2,000
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Alfresa Agreement [Member] | License Agreement [Member] | JAPAN |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 2,000
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License Agreement Expiration Term |
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10 years
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Milestone Payments |
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$ 5,000
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Regulatory milestone payment |
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$ 6,000
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Recordati Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Royalty expense payable |
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$ 100
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$ 100
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Recordati Agreement [Member] | License Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 11,800
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Initial Transaction Price |
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$ 11,800
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Regulatory milestone payment |
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$ 6,000
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$ 6,000
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Recordati Agreement [Member] | Termination Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 3,300
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€ 3.0
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Aggregate milestone payments |
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$ 5,900
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€ 5.0
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Estimated Life of Finite Lived Intangible Assets |
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13 years 6 months
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13 years 6 months
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13 years 6 months
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Contract with Customer, Liability, Revenue Recognized |
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$ 0
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Recordati Agreement [Member] | Research and development [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Milestone Payments |
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$ 2,100
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€ 2.0
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Recordati Agreement [Member] | Research and development [Member] | Termination Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment | € |
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€ 3.0
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Contract with Customer, Liability |
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$ 3,100
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Recordati Agreement [Member] | European Medicines Agency [Member] | Termination Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Milestone Payments | € |
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2.0
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Recordati Agreement [Member] | First commercial sale of Recordati Licensed Product [Member] | Termination Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Milestone Payments | € |
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5.0
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Recordati Agreement [Member] | Aggregate sale of Recordati Licensed Product [Member] | Termination Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Royalty payments | € |
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€ 5.0
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Pediatrix Agreement [Member] | License Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 3,000
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License Agreement Expiration Term |
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10 years
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Initial Transaction Price |
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$ 3,000
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Contract with Customer, Liability, Revenue Recognized |
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$ 3,000
|
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Regulatory and Commercial Sales Milestones |
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84,000
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Pediatrix Agreement [Member] | License Agreement [Member] | CHINA |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Regulatory milestone payment |
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$ 4,000
|
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Seqirus Agreement [Member] | License Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 500
|
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Initial Transaction Price |
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$ 500
|
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Contract with Customer, Liability, Revenue Recognized |
|
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$ 1,500
|
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500
|
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Regulatory and Commercial Sales Milestones |
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$ 4,500
|
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ALK Collaboration Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Contract with Customer, Liability, Revenue Recognized |
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$ (240)
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Accounts receivable |
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$ 5,500
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$ 5,500
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5,500
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Contract with Customer, Liability |
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1,849
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1,849
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1,849
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2,089
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Commercial milestone payments |
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5,000
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ALK Collaboration Agreement [Member] | ALK Financing Liability [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Contract with Customer, Liability |
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71,959
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71,959
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71,959
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$ 69,383
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Increase to the financing liability |
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2,400
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2,435
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Royalty income not recognized |
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100
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ALK Collaboration Agreement [Member] | License Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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$ 145,000
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License Agreement Expiration Term |
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15 years
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Regulatory milestone payment |
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15,000
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Commercial milestone payments |
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5,000
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Contingent Sales-Based Milestones |
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$ 55,000
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Purchase Commitment Period |
5 years
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ALK Collaboration Agreement [Member] | License Agreement [Member] | Maximum [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Regulatory milestone payment |
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15,000
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Sales-Based Milestones |
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300,000
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ALK Collaboration Agreement [Member] | Development and Regulatory Services [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Contract with Customer, Liability, Revenue Recognized |
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$ 500
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100
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200
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Contract liability, current |
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700
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700
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700
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Contract liability, noncurrent |
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1,100
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1,100
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1,100
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ALK Collaboration Agreement [Member] | First Commercial Sale Of Neffy [Member] | License Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Upfront Payment |
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5,000
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ALK Collaboration Agreement [Member] | First Commercial Sale Of Neffy [Member] | Commercial Milestone [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Contract with Customer, Liability, Revenue Recognized |
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2,600
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2,600
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ALK Co-Promotion Agreement [Member] |
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |
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Number of pediatricians | Doctor |
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9,000
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Performance based bonus payments percentage |
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30.00%
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Transaction under agreement with A.L.K U.S |
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Payments to ALK U.S. for the services performed during the first year of the arrangement will be deferred and paid in the second year of the arrangement. In addition to the base fee, ALK U.S. will be eligible to receive performance-based bonus payments from the Company starting in the second year of the arrangement equal to 30% of the portion of neffy net sales generated from the ALK U.S.-targeted prescribers in excess of a specified initial market share threshold in year two or a 50% market share threshold during years three and four of the arrangement.
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Threshold percentage |
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50.00%
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Selling, general and administrative expenses related party amount |
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1,400
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1,400
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Other accrued liabilities |
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$ 1,400
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$ 1,400
|
|
$ 1,400
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