| Schedule of Segment Reporting Information, by Segment |
The following table is the summary of the segment profit or loss information, including the significant expense categories for the three and six months ended June 30, 2025 and 2024, respectively: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | 2025 | | 2024 | | 2025 | | 2024 | | Total revenues, net | | $ | 18,839 | | | $ | 17,410 | | | $ | 41,872 | | | $ | 35,463 | | | Significant operating expenses: | | | | | | | | | | Cost of product sales | | (836) | | | (1,217) | | | (2,897) | | | (3,727) | | Research and development(1) | | (29,605) | | | (23,887) | | | (57,540) | | | (50,172) | | Selling and marketing(1) | | (9,760) | | | (10,504) | | | (20,077) | | | (22,534) | | General and administrative(1) | | (7,632) | | | (8,855) | | | (16,395) | | | (19,538) | | | Restructuring and impairment expenses | | (13,091) | | | — | | | (13,091) | | | — | | | Share-based compensation | | (2,062) | | | (1,988) | | | (4,483) | | | (2,146) | | | Total operating expenses | | (62,986) | | | (46,451) | | | (114,483) | | | (98,117) | | | Loss from operations | | (44,147) | | | (29,041) | | | (72,611) | | | (62,654) | | Other segment items(2) | | (12,499) | | | (7,503) | | | (22,637) | | | (20,496) | | | Net loss | | $ | (56,646) | | | $ | (36,544) | | | $ | (95,248) | | | $ | (83,150) | |
(1)Excludes share-based compensation. (2)Includes Other expense, net, Income tax expense and Equity in net losses of joint venture.
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