​

​

Three months ended

​

Six months ended

​

​

June 30, 

​

June 30, 

​

2025

2024

2025

2024

​

​

​

​

​

​

​

​

​

​

​

​

​

Product revenue, net

​

$

120

​

$

1,104

​

$

288

​

$

1,686

Less:

​

​

​

​

​

​

​

​

​

​

​

​

Cost of goods sold

​

$

107

​

$

62

​

$

121

​

$

141

Research and development costs:

​

​

​

​

​

​

​

​

​

​

​

​

Personnel and related costs

​

$

1,585

​

$

3,195

​

$

3,267

​

$

6,825

Non-cash stock-based compensation

​

​

648

​

​

282

​

​

134

​

​

1,563

Professional fees

​

​

1,007

​

​

1,455

​

​

1,786

​

​

2,763

Clinical trials expense

​

​

6,119

​

​

1,832

​

​

8,137

​

​

5,900

Chemical, manufacturing and controls cost

​

​

535

​

​

778

​

​

710

​

​

1,326

Other expenses

​

​

362

​

​

490

​

​

776

​

​

1,056

Total research and development costs

​

$

10,256

​

$

8,032

​

$

14,810

​

$

19,433

Commercial costs:

​

​

​

​

​

​

​

​

​

​

​

​

Personnel and related costs

​

​

84

​

​

803

​

​

163

​

​

1,952

Non-cash stock-based compensation

​

​

—

​

​

(104)

​

​

—

​

​

164

Professional fees

​

​

138

​

​

30

​

​

176

​

​

102

Commercial and marketing

​

​

38

​

​

(718)

​

​

207

​

​

629

Travel related expenses

​

​

12

​

​

86

​

​

21

​

​

203

Other expenses

​

​

(45)

​

​

218

​

​

(133)

​

​

414

Total commercial costs

​

$

227

​

$

315

​

$

434

​

$

3,464

Selling, general and administrative costs:

​

​

​

​

​

​

​

​

​

Personnel and related costs

​

​

946

​

​

1,699

​

$

1,939

​

$

3,736

Non-cash stock-based compensation

​

​

908

​

​

879

​

1,602

​

​

2,763

Professional fees

​

​

2,572

​

​

5,442

​

5,406

​

​

10,682

Travel related expenses

​

​

132

​

​

2

​

​

248

​

​

249

Other expenses

​

​

824

​

​

1,113

​

1,679

​

​

1,821

Total selling, general and administrative costs

​

$

5,382

​

$

9,135

​

$

10,874

​

$

19,251

Restructuring costs

​

​

—

​

​

856

​

​

—

​

​

856

Total operating expenses

​

$

15,972

​

$

18,400

​

$

26,239

​

$

43,145

Other (income) expense

​

​

​

​

​

​

Interest expense

​

4,222

​

3,700

​

8,215

​

7,307

Interest income

​

​

(230)

​

​

(671)

​

​

(509)

​

​

(1,618)

Other (income) expense, net

​

​

(657)

​

​

(12,026)

​

​

(7,216)

​

​

(12,058)

Segment net loss

​

$

(19,187)

​

$

(8,299)

​

$

(26,441)

​

$

(35,090)

Adjustments and reconciling items

​

​

—

​

​

—

​

​

—

​

​

—

Consolidated Net Loss

​

$

(19,187)

​

$

(8,299)

​

$

(26,441)

​

$

(35,090)