​

​

Three Months Ended June 30,

​

Six Months Ended June 30,

(in thousands)

​

2025

2024

​

2025

2024

Research and development

​

​

​

​

​

​

​

​

​

​

​

​

Wages, benefits and other payroll

​

$

1,302

​

$

2,944

​

$

4,891

​

$

6,355

Third-party costs

​

​

4,154

​

​

6,067

​

​

7,948

​

​

12,679

Share-based compensation

​

​

248

​

​

725

​

​

492

​

​

1,543

Depreciation and amortization

​

​

110

​

​

694

​

​

220

​

​

1,388

Total research and development expenses

​

​

5,814

​

​

10,430

​

​

13,551

​

​

21,965

General and administrative

​

​

​

​

​

​

​

​

​

​

​

​

Wages, benefits and other payroll

​

​

1,798

​

​

2,240

​

​

4,588

​

​

4,540

Third-party costs

​

​

1,974

​

​

3,314

​

​

4,577

​

​

6,640

Share-based compensation

​

​

675

​

​

853

​

​

1,289

​

​

1,630

Depreciation and amortization

​

​

73

​

​

103

​

​

151

​

​

215

Total general and administrative expenses

​

​

4,520

​

​

6,510

​

​

10,605

​

​

13,025

Impairment of long-lived assets

​

​

—

​

​

438

​

​

2,637

​

​

438

Loss from operations

​

​

10,334

​

​

17,378

​

​

26,793

​

​

35,428

Other (income) expense, net

​

​

(949)

​

​

(1,387)

​

​

(2,003)

​

​

(2,726)

Net loss

​

$

9,385

​

$

15,991

​

$

24,790

​

$

32,702