v3.25.2
Segment Information
6 Months Ended
Jun. 30, 2025
Segment Information  
Segment Information

14.Segment Information

The Company manages its operations on a consolidated basis as a single reportable segment focused on the research and development of precision immunology-based therapies. The accounting policies of the single reportable segment are identical to those described in Note 2, Summary of Significant Accounting Policies. When evaluating the Company’s financial performance, the Company’s chief operating decision-maker (the “CODM”), its Chief Executive Officer regularly reviews consolidated net loss, total expense and direct expenses by program and compared to budget. The CODM allocates resources based on the Company’s available cash resources, forecasted expenditures on a consolidated basis, as well as an assessment of the probability of success of its research and development activities on a program basis. Segment asset information regularly provided to the CODM is consistent with that reported on the consolidated balance sheets with particular emphasis on the Company’s available liquidity, including its cash, cash equivalents and investment balances. Revenue is primarily attributed to individual countries based on the entity owning the license. During the three months ended June 30, 2025, the Company did not recognize revenue and for six months ended June 30, 2025, $10.0 million was recognized as revenue which was attributed to Zenas HK. The Company did not recognize revenue during the three or six months ended June 30, 2024.

The following table presents certain financial data for the Company’s reportable segment for the three and six months ended June 30, 2025 and 2024 (in thousands):

For the three months ended June 30,

For the six months ended June 30,

2025

2024

2025

2024

Revenue

$

-

$

-

$

10,000

$

-

Less:

Direct research and development expenses:1

Obexelimab

29,894

22,788

53,254

35,082

Other programs (ZB002 & ZB004)

400

572

736

1,466

Partnered regional programs (ZB001 & ZB005)

(137)

2,435

(37)

4,023

Unallocated research and development2

10,757

7,301

20,295

14,760

General and administrative3

8,204

5,070

16,814

9,466

Stock-based compensation

6,045

1,536

11,431

2,483

Other segment items4

(2,940)

(1,725)

(6,697)

(1,503)

Segment net loss

$

(52,223)

$

(37,977)

$

(85,796)

$

(65,777)

1 Direct research and development expenses primarily consist of direct costs incurred to specific program research and development activities, including costs to conduct clinical trials and to manufacture clinical drug supply.

2 Unallocated research and development expenses primarily consist of indirect costs incurred in support of overall research and development activities and non-specific programs, including activities that benefit multiple programs, such as personnel costs for employees involved in research and development activities, excluding stock-based compensation, as well as contract services not allocated to specific programs.

3 General and administrative expenses primarily consist of professional fees, depreciation expense, facilities expenses as well as all other personnel costs, excluding stock-based compensation.

4 Other segment items consist of other income (expense), net and income tax benefit (provision). Other income (expense), net consists of interest income and realized and unrealized gains and losses on foreign currency transactions.