v3.25.2
Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Total
Underwriter Offering
ATM Program
Ordinary Shares
Ordinary Shares
Underwriter Offering
Ordinary Shares
ATM Program
Additional paid-in capital
Additional paid-in capital
Underwriter Offering
Additional paid-in capital
ATM Program
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2023       98,774,827              
Beginning balance at Dec. 31, 2023 $ 236,244     $ 273     $ 987,423     $ 1,493 $ (752,945)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of ordinary shares, net of issuance costs (in shares)         12,390,254 1,250,000          
Issuance of ordinary shares, net of issuance costs   $ 107,272 $ 9,655   $ 31 $ 3   $ 107,241 $ 9,652    
Stock option exercises (in shares)       302,436              
Stock option exercises 1,647           1,647        
Share-based compensation expense 16,765           16,765        
Vesting of ordinary shares (in shares)       763,151              
Vesting of ordinary shares 0     $ 2     (2)        
Shares withheld to pay employee withholding tax on share-based compensation (in shares)       (302,904)              
Shares withheld to pay employee withholding tax on share-based compensation (2,858)           (2,858)        
Foreign currency translation adjustments (86)                 (86)  
Unrealized (loss) gain on available for sale securities, net of tax 1,406                 1,406  
Reclassification adjustment for realized net gain on available for sale marketable securities included in net loss, net of tax (1,218)                 (1,218)  
Net loss (81,862)                   (81,862)
Ending balance (in shares) at Jun. 30, 2024       113,177,764              
Ending balance at Jun. 30, 2024 286,965     $ 309     1,119,868     1,595 (834,807)
Beginning balance (in shares) at Mar. 31, 2024       100,481,993              
Beginning balance at Mar. 31, 2024 215,163     $ 277     1,004,254     1,623 (790,991)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of ordinary shares, net of issuance costs (in shares)         12,390,254            
Issuance of ordinary shares, net of issuance costs   $ 107,272     $ 31     $ 107,241      
Stock option exercises (in shares)       125,976              
Stock option exercises 692           692        
Share-based compensation expense 8,611           8,611        
Vesting of ordinary shares (in shares)       282,225              
Vesting of ordinary shares       $ 1     (1)        
Shares withheld to pay employee withholding tax on share-based compensation (in shares)       (102,684)              
Shares withheld to pay employee withholding tax on share-based compensation (929)           (929)        
Foreign currency translation adjustments (61)                 (61)  
Unrealized (loss) gain on available for sale securities, net of tax 33                 33  
Net loss (43,816)                   (43,816)
Ending balance (in shares) at Jun. 30, 2024       113,177,764              
Ending balance at Jun. 30, 2024 $ 286,965     $ 309     1,119,868     1,595 (834,807)
Beginning balance (in shares) at Dec. 31, 2024 132,631,587     132,631,587              
Beginning balance at Dec. 31, 2024 $ 401,545     $ 359     1,385,675     4,213 (988,702)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of ordinary shares, net of issuance costs (in shares)           372,538          
Issuance of ordinary shares, net of issuance costs     $ 6,109     $ 1     $ 6,108    
Stock option exercises (in shares) 592,326     592,326              
Stock option exercises $ 3,527     $ 2     3,525        
Share-based compensation expense 15,832           15,832        
Vesting of ordinary shares (in shares)       495,318              
Vesting of ordinary shares       $ 1     (1)        
Shares withheld to pay employee withholding tax on share-based compensation (in shares)       (178,213)              
Shares withheld to pay employee withholding tax on share-based compensation (2,994)           (2,994)        
Foreign currency translation adjustments 164                 164  
Unrealized (loss) gain on available for sale securities, net of tax 1                 1  
Reclassification adjustment for realized net gain on available for sale marketable securities included in net loss, net of tax (2,787)                    
Net loss $ (76,478)                   (76,478)
Ending balance (in shares) at Jun. 30, 2025 133,913,556     133,913,556              
Ending balance at Jun. 30, 2025 $ 344,919     $ 363     1,408,145     1,591 (1,065,180)
Beginning balance (in shares) at Mar. 31, 2025       133,554,598              
Beginning balance at Mar. 31, 2025 386,247     $ 362     1,398,647     2,075 (1,014,837)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Stock option exercises (in shares)       311,610              
Stock option exercises 1,647     $ 1     1,646        
Share-based compensation expense 7,949           7,949        
Vesting of ordinary shares (in shares)       54,409              
Vesting of ordinary shares 0                    
Shares withheld to pay employee withholding tax on share-based compensation (in shares)       (7,061)              
Shares withheld to pay employee withholding tax on share-based compensation (97)           (97)        
Foreign currency translation adjustments (479)                 (479)  
Unrealized (loss) gain on available for sale securities, net of tax (5)                 (5)  
Net loss $ (50,343)                   (50,343)
Ending balance (in shares) at Jun. 30, 2025 133,913,556     133,913,556              
Ending balance at Jun. 30, 2025 $ 344,919     $ 363     $ 1,408,145     $ 1,591 $ (1,065,180)