Share-based Compensation - Summary of Share-Based Compensation Expense (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||
|---|---|---|---|---|
Jun. 30, 2025 |
Jun. 30, 2024 |
Jun. 30, 2025 |
Jun. 30, 2024 |
|
| Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] | ||||
| Compensation expense recognized | $ 7,949 | $ 8,611 | $ 15,832 | $ 16,765 |
| Stock options | ||||
| Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] | ||||
| Compensation expense recognized | 6,889 | 5,775 | 13,022 | 11,207 |
| Restricted share awards and units | ||||
| Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] | ||||
| Compensation expense recognized | 1,060 | 2,836 | 2,810 | 5,558 |
| Research and development | ||||
| Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] | ||||
| Compensation expense recognized | 4,115 | 4,006 | 8,272 | 7,731 |
| General and administrative | ||||
| Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] | ||||
| Compensation expense recognized | $ 3,834 | $ 4,605 | $ 7,560 | $ 9,034 |