v3.25.2
UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
CASH FLOWS (USED IN)/PROVIDED BY OPERATING ACTIVITIES    
Loss before tax $ (223,928) $ (77,758)
Adjustments for:    
Finance income (22,489) (30,919)
Finance costs 10,283 10,959
Provision for inventory reserve (4,866) 6,425
Loss on asset impairment 970 0
Depreciation of property, plant and equipment 4,567 5,576
Loss on disposal of property, plant and equipment 250 2
Amortization of intangible assets 228 1,251
Depreciation of right-of-use assets 6,258 4,264
Fair value gains on financial assets measured at fair value through profit or loss 0 (201)
Foreign currency exchange loss/(gain), net 165,185 (60,704)
Equity-settled share-based compensation expense 34,643 40,442
Deferred government grant (277) (293)
Cash flows provided by (used in) operations before changes in working capital (29,176) (100,956)
(Increase)/decrease in trade receivables (20,280) 86,977
Increase in prepayments, other receivables and other assets (84,418) (30,341)
Decrease/(increase) in other non-current assets 771 (112)
Government grant received 995 85
Increase in collaboration inventories (6,020) (5,862)
Increase in trade payables [1] 36,035 20,842
(Decrease)/increase in other payables and accruals [1] (17,762) 46,129
Decrease in other non-current liabilities 0 (56)
Decrease in contract liabilities, net (18,502) (20,467)
Increase in pledged deposits, net 0 (71)
Cash used in operations (138,357) (3,832)
Interest income received 37,905 19,285
Income tax paid (15,167) (847)
Interest on lease payments (1,177) (739)
Net cash (used in)/provided by operating activities (116,796) 13,867
CASH FLOWS PROVIDED BY/(USED IN) INVESTING ACTIVITIES    
Purchase of property, plant and equipment (11,226) (9,662)
Prepayment to collaborator for collaboration assets (21,659) (33,695)
Purchase of financial assets measured at fair value through profit or loss 0 (150,560)
Cash received from withdrawal of financial assets measured at fair value through profit or loss 0 108,163
Cash receipts of investment income 0 1,846
Addition in time deposits (4,150,000) (2,194,188)
Decrease in time deposits 4,274,000 1,186,317
Net cash provided by/(used in) investing activities 91,115 (1,091,779)
CASH FLOWS (USED IN)/PROVIDED BY FINANCING ACTIVITIES    
Proceeds from exercise of share options 1,717 3,704
Principal portion of lease payments (2,040) (1,918)
Net cash (used in)/provided by financing activities (323) 1,786
NET DECREASE IN CASH AND CASH EQUIVALENTS (26,004) (1,076,126)
Effect of foreign exchange rate changes, net 5,841 (334)
Cash and cash equivalents at beginning of year 286,749 1,277,713
CASH AND CASH EQUIVALENTS AT END OF PERIOD 266,586 201,253
Analysis of balances of cash and cash equivalents    
Cash and bank balances 967,625 1,254,469
Less: Pledged deposits 70 431
Time deposits 700,969 1,052,785
Cash and cash equivalents as stated in the statement of financial position 266,586 201,253
Cash and cash equivalents as stated in the statement of cash flows $ 266,586 $ 201,253
[1] Certain prior year amounts have been reclassified between increase in trade payables and (decrease)/increase in other payables and accruals for comparative purposes