| Schedule of Segment Reporting Information, by Segment [Table Text Block] |
| |
|
Three Months Ended June 30,
|
|
|
Six Months Ended June 30,
|
|
| |
|
2025
|
|
|
2024
|
|
|
2025
|
|
|
2024
|
|
| |
|
(000's)
|
|
|
(000's)
|
|
|
Licensing revenue
|
|
$ |
— |
|
|
$ |
850 |
|
|
$ |
— |
|
|
$ |
850 |
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Personnel
|
|
|
2,417 |
|
|
|
1,932 |
|
|
|
5,187 |
|
|
|
3,769 |
|
|
General
|
|
|
1,709 |
|
|
|
1,396 |
|
|
|
3,358 |
|
|
|
3,317 |
|
|
Tovecimig
|
|
|
7,749 |
|
|
|
6,413 |
|
|
|
14,426 |
|
|
|
10,911 |
|
|
CTX-471
|
|
|
1,760 |
|
|
|
828 |
|
|
|
2,459 |
|
|
|
1,507 |
|
|
CTX-8371
|
|
|
1,044 |
|
|
|
605 |
|
|
|
1,573 |
|
|
|
1,191 |
|
|
CTX-10726
|
|
|
1,736 |
|
|
|
— |
|
|
|
2,473 |
|
|
|
— |
|
|
Research and development
|
|
|
16,415 |
|
|
|
11,174 |
|
|
|
29,476 |
|
|
|
20,695 |
|
|
Personnel
|
|
|
1,168 |
|
|
|
1,801 |
|
|
|
2,763 |
|
|
|
2,745 |
|
|
General
|
|
|
1,549 |
|
|
|
1,257 |
|
|
|
3,152 |
|
|
|
2,482 |
|
|
Stock-based compensation
|
|
|
1,934 |
|
|
|
1,663 |
|
|
|
3,641 |
|
|
|
2,742 |
|
|
General and administrative
|
|
|
4,651 |
|
|
|
4,721 |
|
|
|
9,556 |
|
|
|
7,969 |
|
|
Other income
|
|
|
1,185 |
|
|
|
1,969 |
|
|
|
2,518 |
|
|
|
3,951 |
|
|
Net loss
|
|
$ |
(19,881 |
) |
|
$ |
(13,076 |
) |
|
$ |
(36,514 |
) |
|
$ |
(23,863 |
) |
|