v3.25.2
Segment Information - Schedule of Significant Segment Expense Categories (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]            
Research and development personnel-related expense $ (46,319)   $ (23,485)   $ (74,082) $ (47,189)
Stock-based compensation expense (8,420)   (4,091)   (14,783) (8,149)
Net loss (55,247) $ (34,085) (26,352) $ (26,949) (89,332) (53,301)
Significant Segment Expense Category [Member]            
Segment Reporting Information [Line Items]            
Commercial expense (2,660)   (304)   (4,581) (505)
General and administrative expense (7,873)   (4,457)   (14,731) (9,700)
Stock-based compensation expense (8,420)   (4,091)   (14,783) (8,149)
Other Segment Items [Member]            
Segment Reporting Information [Line Items]            
Other segment items 6,163   4,500   12,024 9,013
Key Measure of Segment Profit or Loss [Member]            
Segment Reporting Information [Line Items]            
Net loss (55,247)   (26,352)   (89,332) (53,301)
Bitopertin [Member] | Significant Segment Expense Category [Member]            
Segment Reporting Information [Line Items]            
Research and development personnel-related expense (23,686)   (7,112)   (32,121) (13,481)
DISC-0974 [Member] | Significant Segment Expense Category [Member]            
Segment Reporting Information [Line Items]            
Research and development personnel-related expense (4,615)   (3,289)   (10,736) (7,060)
DISC-3405 [Member] | Significant Segment Expense Category [Member]            
Segment Reporting Information [Line Items]            
Research and development personnel-related expense (1,908)   (3,868)   (3,576) (8,569)
Other Research [Member] | Significant Segment Expense Category [Member]            
Segment Reporting Information [Line Items]            
Research and development personnel-related expense (3,103)   (1,938)   (4,935) (3,658)
Internal Research and Development [Member] | Significant Segment Expense Category [Member]            
Segment Reporting Information [Line Items]            
Research and development personnel-related expense $ (9,145)   $ (5,793)   $ (15,893) $ (11,192)