v3.25.2
Segment Information
 6 Months Ended
Jun. 30, 2025
Segment Reporting [Abstract]  
Segment Information

13. Segment Information

The Company manages its operations as a single operating segment for the purposes of assessing performance and making operating decisions, resulting in a single reportable segment. The Company has determined that its Chief Operating Decision Maker ("CODM") is its Chief Executive Officer. The Company’s CODM reviews the Company’s financial information on a consolidated basis for the purpose of allocating resources and assessing financial performance.

The key measure of segment profit or loss that the CODM uses to allocate resources and assess performance is the Company’s consolidated net loss, as reported on the condensed consolidated statements of operations and comprehensive loss. In addition, the CODM is regularly provided the significant segment expense categories included in the table below, which are reviewed against budgeted expectations to assist in resource allocation decision-making. The categories reflect a change made during the first quarter of 2025 to separately present commercial expense. The prior periods have been recast to reflect this update.

 

Three months ended June 30,

 

 

Six months ended June 30,

 

 

2025

 

 

2024

 

 

2025

 

 

2024

 

Bitopertin program external expense

 

$

(23,686

)

 

$

(7,112

)

 

$

(32,121

)

 

$

(13,481

)

DISC-0974 program external expense

 

 

(4,615

)

 

 

(3,289

)

 

 

(10,736

)

 

 

(7,060

)

DISC-3405 program external expense

 

 

(1,908

)

 

 

(3,868

)

 

 

(3,576

)

 

 

(8,569

)

Other external research and development expense

 

 

(3,103

)

 

 

(1,938

)

 

 

(4,935

)

 

 

(3,658

)

Internal and other research and development expense

 

 

(9,145

)

 

 

(5,793

)

 

 

(15,893

)

 

 

(11,192

)

 

 

 

 

 

 

 

 

 

 

 

 

 

Commercial expense

 

$

(2,660

)

 

$

(304

)

 

$

(4,581

)

 

$

(505

)

 

 

 

 

 

 

 

 

 

 

 

 

 

General and administrative expense

 

$

(7,873

)

 

$

(4,457

)

 

$

(14,731

)

 

$

(9,700

)

 

 

 

 

 

 

 

 

 

 

 

 

 

Stock-based compensation expense

 

$

(8,420

)

 

$

(4,091

)

 

$

(14,783

)

 

$

(8,149

)

 

 

 

 

 

 

 

 

 

 

 

 

 

Other segment items*

 

$

6,163

 

 

$

4,500

 

 

$

12,024

 

 

$

9,013

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net loss

 

$

(55,247

)

 

$

(26,352

)

 

$

(89,332

)

 

$

(53,301

)

*Other segment items include interest income, interest expense, other expense, and income tax expense as reported on the condensed consolidated statements of operations and comprehensive loss.

Assets regularly provided to the CODM are consistent with those reported on the condensed consolidated balance sheets with particular emphasis on the Company’s available liquidity, including its cash, cash equivalents and marketable securities balances. All of the Company’s tangible assets are held in the United States.