v3.25.2
Cover - shares
 6 Months Ended
Jun. 30, 2025
Jul. 31, 2025
Cover [Abstract]    
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Jun. 30, 2025  
Document Transition Report false  
Entity File Number 001-41536  
Entity Registrant Name Prime Medicine, Inc.  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 84-3097762  
Entity Address, Address Line One 60 First Street  
Entity Address, City or Town Cambridge  
Entity Address, State or Province MA  
Entity Address, Postal Zip Code 02141  
City Area Code (617)  
Local Phone Number 465-0013  
Title of 12(b) Security Common stock, par value $0.00001 per share  
Trading Symbol PRME  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company true  
Entity Ex Transition Period false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   134,573,998
Entity Central Index Key 0001894562  
Amendment Flag false  
Document Fiscal Year Focus 2025  
Document Fiscal Period Focus Q2  
Current Fiscal Year End Date --12-31