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SEGMENTS
 6 Months Ended
Jun. 30, 2025
Segment Reporting [Abstract]  
SEGMENTS SEGMENTS
The Company defines its segments on the basis of the way in which internally reported financial information is regularly reviewed by the chief operating decision maker ("CODM") to analyze financial performance, make decisions, and allocate resources. The Company’s CODM consists of its Chief Executive Officer, Chief Financial Officer and Chief Medical Officer. The Company manages its operations as a single operating and reportable segment and the measure of segment profit or loss is net loss and comprehensive loss. The CODM uses net
loss in the budget and forecasting process and considers budget-to-actual variances on a quarterly basis when making decisions about the allocation of operating and capital resources.
The following table summarizes the information about reported segment revenues and significant segment expenses presented on the Company's condensed consolidated statements of operations and comprehensive loss for the three and six months ended 2025 and 2024:

FOR THE THREE MONTHS ENDED
JUNE 30,		FOR THE SIX MONTHS ENDED
JUNE 30,
(in thousands)2025202420252024
Revenue$212 $299 $424 $299 
Less:
Research and development:
RLYB2121,377 6,834 3,815 12,479 
RLYB1161,274 3,140 1,893 4,437 
Other program candidates95 578 (68)1,182 
Personnel expenses (including share-based compensation)3,161 2,154 5,750 7,325 
Other expenses167 240 409 459 
Total research and development6,074 12,946 11,799 25,882 
General and administrative, excluding personnel expenses1,472 1,821 2,997 3,732 
General and administrative, personnel expenses (including share-based compensation)2,723 2,567 5,355 7,507 
Other segment items*(354)(799)(585)(1,557)
Segment net loss$(9,703)$(16,236)$(19,142)$(35,265)

*Other segment items include total other income, net and loss on investment in joint venture.