Schedule of Segment Net Loss, Including Disaggregated Components of Operating Expenses |
The Company's consolidated and segment net loss, including disaggregated components of operating expenses is as follows (in thousands):
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended June 30, |
|
|
|
Six Months Ended June 30, |
|
|
|
|
|
|
|
|
|
2025 |
|
|
2024 |
|
|
|
2025 |
|
|
2024 |
|
Collaboration revenue |
|
|
|
|
|
|
|
$ |
937 |
|
|
$ |
510 |
|
|
|
$ |
1,503 |
|
|
$ |
1,150 |
|
Operating expenses: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Research and development: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Verekitug program: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Asthma indication |
|
|
|
|
|
|
|
|
13,236 |
|
|
|
6,935 |
|
|
|
|
23,257 |
|
|
|
13,102 |
|
COPD indication |
|
|
|
|
|
|
|
|
6,803 |
|
|
|
— |
|
|
|
|
12,490 |
|
|
|
— |
|
CRSwNP indication |
|
|
|
|
|
|
|
|
2,238 |
|
|
|
2,072 |
|
|
|
|
5,001 |
|
|
|
3,636 |
|
Manufacturing costs |
|
|
|
|
|
|
|
|
10,000 |
|
|
|
1,416 |
|
|
|
|
12,129 |
|
|
|
1,641 |
|
Personnel expenses |
|
|
|
|
|
|
|
|
4,509 |
|
|
|
2,404 |
|
|
|
|
8,214 |
|
|
|
4,839 |
|
Professional fees and other |
|
|
|
|
|
|
|
|
1,079 |
|
|
|
1,242 |
|
|
|
|
2,571 |
|
|
|
2,542 |
|
Total research and development expenses |
|
|
|
|
|
|
|
|
37,865 |
|
|
|
14,069 |
|
|
|
|
63,662 |
|
|
|
25,760 |
|
General and administrative: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Personnel expenses |
|
|
|
|
|
|
|
|
3,773 |
|
|
|
2,313 |
|
|
|
|
8,005 |
|
|
|
4,689 |
|
Professional fees |
|
|
|
|
|
|
|
|
2,397 |
|
|
|
1,334 |
|
|
|
|
3,893 |
|
|
|
2,461 |
|
Other |
|
|
|
|
|
|
|
|
1,249 |
|
|
|
334 |
|
|
|
|
2,303 |
|
|
|
793 |
|
Total general and administrative expenses |
|
|
|
|
|
|
|
|
7,419 |
|
|
|
3,981 |
|
|
|
|
14,201 |
|
|
|
7,943 |
|
Total operating expenses |
|
|
|
|
|
|
|
|
45,284 |
|
|
|
18,050 |
|
|
|
|
77,863 |
|
|
|
33,703 |
|
Loss from operations |
|
|
|
|
|
|
|
|
(44,347 |
) |
|
|
(17,540 |
) |
|
|
|
(76,360 |
) |
|
|
(32,553 |
) |
Other income (expense): |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Change in fair value of preferred stock tranche right liability |
|
|
|
|
|
|
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
2,859 |
|
Interest income |
|
|
|
|
|
|
|
|
4,431 |
|
|
|
2,877 |
|
|
|
|
9,174 |
|
|
|
4,143 |
|
Other expense, net |
|
|
|
|
|
|
|
|
(50 |
) |
|
|
(15 |
) |
|
|
|
(50 |
) |
|
|
(21 |
) |
Total other income, net |
|
|
|
|
|
|
|
|
4,381 |
|
|
|
2,862 |
|
|
|
|
9,124 |
|
|
|
6,981 |
|
Segment and consolidated net loss |
|
|
|
|
|
|
|
$ |
(39,966 |
) |
|
$ |
(14,678 |
) |
|
|
$ |
(67,236 |
) |
|
$ |
(25,572 |
) |
|