S-8 S-8 EX-FILING FEES 0001034842 RIGEL PHARMACEUTICALS INC N/A Fees to be Paid Fees to be Paid 0001034842 2025-08-05 2025-08-05 0001034842 1 2025-08-05 2025-08-05 0001034842 2 2025-08-05 2025-08-05 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-8

RIGEL PHARMACEUTICALS INC

Table 1: Newly Registered Securities

Security Type

Security Class Title

Fee Calculation Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

1 Equity Common Stock, $0.001 par value per share 457(a) 125,000 $ 20.66 $ 2,582,500.00 0.0001531 $ 395.38
2 Equity Common Stock, $0.001 par value per share 457(a) 700,000 $ 20.66 $ 14,462,000.00 0.0001531 $ 2,214.13

Total Offering Amounts:

$ 17,044,500.00

$ 2,609.51

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 2,609.51

Offering Note

1

(a) Represents shares of the Registrant's Common Stock that were added to the Rigel Pharmaceuticals, Inc. Inducement Plan, as amended (the "Inducement Plan"), pursuant to share reserve increases approved by the Registrant's Board of Directors. Pursuant to Rule 416(a) promulgated under the Securities Act of 1933, as amended, or the Securities Act, this Registration Statement shall also cover any additional shares of Registrant's Common Stock that become issuable under the Inducement Plan by reason of any stock dividend, stock split, recapitalization, or other similar transaction effected that results in an increase to the number of outstanding shares of Registrant's Common Stock, as applicable. (b) Filing fee is estimated in accordance with Rules 457(c) and 457(h) solely for the purpose of calculating the registration fee on the basis of $20.66 per share, the average of the high and low prices of the Registrant's Common Stock on July 30, 2025 as reported on the Nasdaq Global Select Market.

2

(a) Represents shares of the Registrant's Common Stock that were added to the Rigel Pharmaceuticals, Inc. 2018 Equity Incentive Plan, as amended ("2018 Plan"), pursuant to a share reserve increase approved by the Registrant's Board of Directors and the Registrant's stockholders. Pursuant to Rule 416(a) promulgated under the Securities Act, this Registration Statement shall also cover any additional shares of Registrant's Common Stock that become issuable under the 2018 Plan by reason of any stock dividend, stock split, recapitalization, or other similar transaction effected that results in an increase to the number of outstanding shares of Registrant's Common Stock, as applicable. (b) Filing fee is estimated in accordance with Rules 457(c) and 457(h) solely for the purpose of calculating the registration fee on the basis of $20.66 per share, the average of the high and low prices of the Registrant's Common Stock on July 30, 2025 as reported on the Nasdaq Global Select Market.
Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A