Represents an amount lower than $1 Other segment expense (income) during the six months ended June 30, 2025 and 2024 includes property and equipment depreciation, GS-0321 asset of set-up activities, share-based compensation and other adjustments. 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Exhibit 99.2
 
COMPUGEN LTD. AND ITS SUBSIDIARY
 
INTERIM CONSOLIDATED FINANCIAL STATEMENTS
 
AS OF JUNE 30, 2025
 
U.S. DOLLARS IN THOUSANDS
 
UNAUDITED
 
INDEX
 
 
Page
  
F-2 – F-3
  
F-4
  
F-5
  
F-6
  
F-7 – F-18
 
- - - - - - - - - - - - -

COMPUGEN LTD. AND ITS SUBSIDIARY
INTERIM CONSOLIDATED BALANCE SHEETS (Unaudited)
U.S. dollars in thousands
 
   
June 30,
   
December 31,
 
   
2025
   
2024
 
ASSETS
           
             
CURRENT ASSETS:
           
Cash and cash equivalents
 
$
6,467
   
$
18,229
 
Short-term bank deposits
   
58,535
     
61,397
 
Investment in marketable securities
   
28,875
     
23,629
 
Other accounts receivable and prepaid expenses
   
3,765
     
2,742
 
                 
Total current assets
   
97,642
     
105,997
 
                 
NON-CURRENT ASSETS:
               
Restricted long-term bank deposit
   
371
     
343
 
Long-term prepaid expenses
   
1,738
     
1,888
 
Severance pay fund
   
3,257
     
3,072
 
Operating lease right to use asset
   
2,678
     
2,843
 
Property and equipment, net
   
839
     
852
 
                 
Total non-current assets
   
8,883
     
8,998
 
                 
Total assets
 
$
106,525
   
$
114,995
 
 
The accompanying notes are an integral part of the interim consolidated financial statements.
F - 2

COMPUGEN LTD. AND ITS SUBSIDIARY
INTERIM CONSOLIDATED BALANCE SHEETS (Unaudited)
U.S. dollars in thousands (except share data)
 
   
June 30,
   
December 31,
 
   
2025
   
2024
 
LIABILITIES AND SHAREHOLDERS' EQUITY
           
             
CURRENT LIABILITIES:
           
Trade payables
 
$
1,791
   
$
1,838
 
Deferred revenues
   
10,545
     
9,632
 
Current maturity of operating lease liability
   
471
     
448
 
Accrued expenses
   
4,930
     
5,168
 
Employees and related accruals
   
2,846
     
3,074
 
                 
Total current liabilities
   
20,583
     
20,160
 
                 
NON- CURRENT LIABILITIES:
               
Deferred revenues
   
29,592
     
34,045
 
Operating lease liability
   
2,499
     
2,464
 
Accrued severance pay
   
3,595
     
3,412
 
                 
Total non-current liabilities
   
35,686
     
39,921
 
                 
COMMITMENTS AND CONTINGENT LIABILITIES (NOTE 6)
           
                 
SHAREHOLDERS' EQUITY:
               
Share capital:
               
   Ordinary shares of NIS 0.01 par value: 200,000,000 shares authorized on June 30, 2025, and December 31, 2024; 93,535,357 and 89,541,246 shares issued and outstanding on June 30, 2025, and December 31, 2024, respectively
   
259
     
248
 
Additional paid-in capital
   
553,294
     
543,413
 
Accumulated other comprehensive income (loss)
   
(16
)
   
11
 
Accumulated deficit
   
(503,281
)
   
(488,758
)
                 
Total shareholders' equity
   
50,256
     
54,914
 
                 
Total liabilities and shareholders' equity
 
$
106,525
   
$
114,995
 
 
The accompanying notes are an integral part of the interim consolidated financial statements.
F - 3

COMPUGEN LTD. AND ITS SUBSIDIARY
INTERIM CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited)
U.S. dollars in thousands (except share and per share data)
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
             
Revenues
 
$
3,541
   
$
9,261
 
Cost of revenues
   
4,065
     
3,654
 
                 
Gross profit (loss)
   
(524
)
   
5,607
 
                 
Operating expenses:
               
Research and development expenses
   
11,414
     
12,593
 
Marketing and business development expenses
   
280
     
248
 
General and administrative expenses
   
4,606
     
4,670
 
                 
Total operating expenses
   
16,300
     
17,511
 
                 
Operating loss
   
(16,824
)
   
(11,904
)
                 
Financial and other income, net
   
2,315
     
2,528
 
                 
Loss before taxes on income
   
(14,509
)
   
(9,376
)
Tax expense
   
(14
)
   
(14
)
                 
Net loss
 
$
(14,523
)
 
$
(9,390
)
                 
Other comprehensive loss:                
                 
Change in unrealized gains (losses) on marketable securities:                
       Unrealized losses arising during the period, net
 
$
(27
)
 
$
(25
)
                 
Total comprehensive loss
 
$
(14,550
)
 
$
(9,415
)
                 
Basic and diluted net loss per share
 
$
(0.16
)
 
$
(0.10
)
                 
Weighted average number of ordinary shares used in computing basic and diluted net loss per share
   
92,917,554
     
89,518,778
 
 
The accompanying notes are an integral part of the interim consolidated financial statements.
F - 4

COMPUGEN LTD. AND ITS SUBSIDIARY
INTERIM STATEMENTS OF CHANGES IN SHAREHOLDERS’ EQUITY (Unaudited)
U.S. dollars in thousands (except share data)
 
   
Ordinary shares
   
Additional paid-in
capital
   
Accumulated
other
comprehensive
Income (loss)
   
Accumulated
deficit
    Total shareholders’
equity
 
                     
                     
   
Number
   
Amount
                 
                                     
Balance as of January 1, 2024
   
89,237,465
   
$
247
   
$
539,837
   
$
2
   
$
(474,527
)
 
$
65,559
 
                                                 
Options exercised
   
1,744
     
*
     
1
     
-
     
-
     
1
 
Issuance of shares, net
   
292,728
     
1
     
561
     
-
     
-
     
562
 
Stock-based compensation issued to employees, directors and non-employees
   
-
     
-
     
1,633
     
-
     
-
     
1,633
 
Other comprehensive loss from marketable securities, net
   
-
     
-
     
-
     
(25
)
   
-
     
(25
)
Net loss
   
-
     
-
     
-
     
-
     
(9,390
)
   
(9,390
)
                                                 
Balance as of June 30, 2024 (unaudited)
   
89,531,937
   
$
248
   
$
542,032
   
$
(23
)
 
$
(483,917
)
 
$
58,340
 
                                                 
Balance as of January 1, 2025
   
89,541,246
   
$
248
   
$
543,413
   
$
11
   
$
(488,758
)
 
$
54,914
 
                                                 
Options exercised
   
32,470
     
*
     
35
     
-
     
-
     
35
 
Issuance of shares, net
   
3,961,641
     
11
     
8,859
     
-
     
-
     
8,870
 
Stock-based compensation issued to employees, directors and non-employees
   
-
     
-
     
987
     
-
     
-
     
987
 
Other comprehensive loss from marketable securities, net
   
-
     
-
     
-
     
(27
)
           
(27
)
Net loss
   
-
     
-
     
-
     
-
     
(14,523
)
   
(14,523
)
                                                 
Balance as of June 30, 2025 (unaudited)
   
93,535,357
   
$
259
   
$
553,294
   
$
(16
)
 
$
(503,281
)
 
$
50,256
 
 
*          Represents an amount lower than $1.
 
The accompanying notes are an integral part of the interim consolidated financial statements.
F - 5

COMPUGEN LTD. AND ITS SUBSIDIARY
INTERIM CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited)
U.S. dollars in thousands
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
             
Cash flows from operating activities:
           
Net loss
 
$
(14,523
)
 
$
(9,390
)
                 
Adjustments required to reconcile net loss to net cash used in operating activities:
               
Stock-based compensation
   
987
     
1,633
 
Depreciation
   
235
     
238
 
Amortization of discount on marketable securities
   
(310
)
   
(796
)
Increase (decrease) in severance pay, net
   
(2
)
   
6
 
Exchange rate differences loss (gain) on cash balances
   
(166
)
   
12
 
Decrease in operating lease right of use asset
   
229
     
332
 
Increase in interest receivables and exchange differences on short-term bank deposits
   
(62
)
   
(299
)
Increase in interest receivables and exchange differences on long-term bank deposits
   
(28
)
   
-
 
Decrease in trade receivables
   
-
     
56,000
 
Increase in other accounts receivable and prepaid expenses
   
(1,023
)
   
(2,267
)
Decrease in long-term prepaid expenses
   
150
     
311
 
Decrease in trade payables
   
(39
)
   
(1,137
)
Decrease in other accounts payable and accrued expenses
   
(466
)
   
(293
)
Decrease in operating lease liability
   
(6
)
   
(386
)
Decrease in deferred revenues
   
(3,540
)
   
(4,261
)
Net cash provided by (used in) operating activities
   
(18,564
)
   
39,703
 
                 
Cash flows from investing activities:
               
Proceeds from maturity of short-term bank deposits
   
40,896
     
25,011
 
Investment in short-term bank deposits
   
(37,972
)
   
(47,086
)
Proceeds from maturity of marketable securities
   
21,643
     
15,825
 
Investment in marketable securities
   
(26,606
)
   
(36,000
)
Purchase of property and equipment
   
(230
)
   
(37
)
Net cash used in investing activities
   
(2,269
)
   
(42,287
)
                 
Cash flows from financing activities:
               
Proceeds from issuance of ordinary shares, net
   
8,870
     
562
 
Proceeds from exercise of options
   
35
     
1
 
Net cash provided by financing activities
   
8,905
     
563
 
                 
Effect of exchange rate changes on cash
   
166
     
(12
)
                 
Decrease in cash, cash equivalents and restricted cash
   
(11,762
)
   
(2,033
)
Cash, cash equivalents and restricted cash at the beginning of the period
   
18,229
     
13,910
 
Cash, cash equivalents and restricted cash at the end of the period
 
$
6,467
   
$
11,877
 
                 
Supplemental disclosure of non-cash investing and financing activities:
               
                 
Purchase of property and equipment
 
$
(8
)
 
$
13
 
Right-of-use asset obtained in exchange for operating lease liability
 
$
64
   
$
2,064
 
 
The accompanying notes are an integral part of the interim consolidated financial statements.

 

F - 6


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 1:-
GENERAL
 
  a.
Compugen (the “Company”) is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive AI/ML-powered computational discovery platform (Unigen) to identify new drug targets and biological pathways for developing cancer immunotherapies. Compugen has two proprietary product candidates in Phase 1 development: COM701, a potential first-in-class anti-PVRIG antibody and COM902, a potential best-in-class antibody targeting TIGIT for the treatment of solid tumors. Rilvegostomig, a PD-1/TIGIT bispecific antibody where the TIGIT component is derived from Compugen’s clinical stage anti-TIGIT antibody, COM902, is in Phase 3 development by AstraZeneca through a license agreement for the development of bispecific and multispecific antibodies. GS-0321 (previously COM503), a potential first-in-class, high affinity anti-IL-18 binding protein antibody, which is in Phase 1 development is licensed to Gilead. In addition, the Company’s therapeutic pipeline of early-stage immuno-oncology programs consists of research programs aiming to address new mechanisms to activate the immune system against cancer.
 
  b.
The Company is headquartered in Holon, Israel. Its clinical development activities operate from the Company’s headquarters in Israel and from its U.S. subsidiary in San Francisco, California.
 
  c.
The Company has incurred losses in the amount of $14,523 during the six months ended June 30, 2025, has an accumulated deficit of $503,281 as of June 30, 2025, and has an accumulated negative cash flow from operating activities in the amount of $18,564 for the six months ended June 30, 2025. The Company believes that its existing capital resources will be adequate to satisfy its expected liquidity requirements at the current level of yearly expenditures at least twelve months from the reporting date.

 

F - 7


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 1:-
GENERAL (Cont.)
   
  d.
Effective March 30, 2018, the Company entered into an exclusive license agreement with MedImmune Limited, the global biologics research and development arm of AstraZeneca (“AstraZeneca”) to enable the development of bi-specific and multi-specific immuno-oncology antibody products. Under the terms of the agreement, Compugen provided an exclusive license to AstraZeneca for the development of bi-specific and multi-specific antibody products derived from COM902. AstraZeneca has the right to create multiple products under this license and is solely responsible for all research, development and commercial activities under the agreement. In connection with such license agreement, AstraZeneca developed rilvegostomig, a novel PD-1/TIGIT bi-specific antibody with a TIGIT component that is derived from our COM902. Rilvegostomig entered the clinic in September 2021, the first patient dosing in the first indication of its Phase 3 study took place in December 2023, and the first patient dosing in the second indication Phase 3 study took place in May 2024. Compugen received a $10,000 upfront payment and $30,500 milestone payments out of up to $200,000 that the Company is eligible to receive in development, regulatory and commercial milestones for the first product as well as tiered royalties on future product sales. If additional products are developed, additional milestones and royalties would be due to Compugen for each product.
 
  e.
On December 18, 2023, the Company entered into an exclusive license agreement (the “License Agreement”) with Gilead Sciences, Inc. (“Gilead”) pursuant to which the Company granted Gilead an exclusive license under the Company’s then pre-clinical antibody program against IL-18 binding protein and all intellectual property rights subsisting therein, to use, research, develop, manufacture and commercialize products, including the Company’s COM503 product candidate, now named GS-0321, and additional products that may be so developed by Gilead (together with GS-0321, the “Licensed Products”).
 
Pursuant to the License Agreement, Gilead paid the Company a one-time, upfront payment of $60,000 in January 2024. The Company has continued to develop GS-0321 during the initial development term, which included conducting activities defined within the agreement to advance GS-0321 through the clearance of an investigational new drug application (“IND”) and further. Gilead paid to the Company $30,000 in the form of a milestone payment upon clearance of the IND for GS-0321. The Company is also eligible to receive up to approximately $758,000 in additional milestone payments upon the achievement of certain development, regulatory and commercial milestones. The Company is further eligible to receive a single-digit to low double-digit tiered royalties on worldwide net sales of Licensed Products.
 
The Company is responsible for conducting a Phase 1 clinical trial for GS-0321, including handling the regulatory matters in connection therewith, and will bear the costs of such trial (including the GS-0321 drug supply), with Gilead providing at no cost its zimberelimab antibody for such trial. In certain circumstances, Gilead may assume the role of conducting the Phase 1 clinical trial.
 
Upon completion of the Phase 1 clinical trial for GS-0321, the Company will initiate the transfer of development activities related to GS-0321 to Gilead, following which, Gilead will have sole responsibility to develop and commercialize the Licensed Products.

 

F - 8


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 1:-
GENERAL (Cont.)
   
During the term of the License Agreement, the Company is prohibited from researching, developing, making, and commercializing any compounds, molecules, products or treatment methods that are directed to IL-18 or any companion diagnostics for an IL-18 product.
 
Unless terminated early by a party pursuant to its terms, the License Agreement will continue in effect on a Licensed Product-by-Licensed Product and country-by-country basis until the expiration of the last royalty term in such country.
 
Gilead withheld at source 15% from the upfront payment and IND clearance milestone amounts paid to the Company in January 2024 and in September 2024, respectively, and is expected to continue and withhold at source all taxes required by law from all payments payable to the Company under the License Agreement.
 
The License Agreement contains customary representations, warranties, covenants, and terms governing the prosecution and enforcement of certain intellectual property and issues related to technology transfer, manufacturing transfer, provisions with respect to establishment of joint steering committee and its governance covenants with respect to change of control and others.

 

NOTE 2:-
SIGNIFICANT ACCOUNTING POLICIES
 
These unaudited interim consolidated financial statements should be read in conjunction with the audited consolidated financial statements and accompanying notes for the year ended December 31, 2024. The significant accounting policies applied in the annual consolidated financial statements of the Company as of December 31, 2024, are applied consistently in these interim consolidated financial statements.
 
Recently adopted accounting pronouncements
 
In December 2023, the FASB issued ASU 2023-09, Income Taxes (Topic 740): Improvements to Income Tax Disclosures, which requires public entities, on an annual basis, to provide disclosure of specific categories in the rate reconciliation, as well as disclosure of income taxes paid disaggregated by jurisdiction. ASU 2023-09 is effective for fiscal years beginning after December 15, 2024, with early adoption permitted. The Company is currently evaluating the impact of adopting ASU 2023-09.
 

F - 9


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 2:-
SIGNIFICANT ACCOUNTING POLICIES (Cont.)
   
Recently issued accounting pronouncements
 
In November 2024, the FASB issued ASU 2024-03, Income Statement - Reporting Comprehensive Income - Expense Disaggregation Disclosure (Subtopic 220-40), Disaggregation of Income Statement Expenses, which requires disclosure of disaggregated information about certain expense captions presented in the Consolidated Statements of Operations as well as disclosure about selling expense. The guidance will be effective for the Company for annual periods beginning January 1, 2027 and interim periods beginning January 1, 2028, with early adoption permitted. It could be applied either prospectively or retrospectively. The Company is currently evaluating the impact on its financial statement disclosures.

 

NOTE 3:-
UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS
 
The accompanying unaudited interim consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States for interim financial information. Accordingly, they do not include all the information and footnotes required by accounting principles generally accepted in the United States for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included.
 
Operating results for the six-month period ended June 30, 2025, are not necessarily indicative of the results that may be expected for the year ended December 31, 2025.
 
NOTE 4:-
MARKETABLE SECURITIES
 
The following is a summary of available-for-sale marketable securities as of June 30, 2025 and December 31, 2024:
 
   
Amortized cost
   
Gross unrealized gains
   
Gross unrealized losses
   
Fair value
 
As of June 30, 2025:
                       
Available-for-sale – matures within one year:
                       
Governmental bonds
 
$
28,891
   
$
-
   
$
16
   
$
28,875
 
                                 
As of December 31, 2024:
                               
Available-for-sale – matures within one year:
                               
Governmental bonds
 
$
23,618
   
$
11
   
$
-
   
$
23,629
 

 

F - 10


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 4:-
MARKETABLE SECURITIES (Cont.)
   
The following table presents gross unrealized losses and fair values for those investments that were in an unrealized loss position as of June 30, 2025 and December 31, 2024, and the length of time that those investments have been in a continuous loss position:
 
   
Less than 12 months
   
12 months or greater
 
   
Fair value
   
Gross unrealized loss
   
Fair value
   
Gross unrealized loss
 
                         
As of June 30, 2025
 
$
28,875
   
$
16
   
$
-
   
$
-
 
                                 
As of December 31, 2024
 
$
-
   
$
-
   
$
-
   
$
-
 
 
As of June 30, 2025, the Company had no significant unrealized losses related to marketable securities (which were accumulated in a period of less than 12 months) and determined the unrealized losses are not due to credit related losses, therefore, the Company did not record an allowance for credit losses for its available-for-sale marketable securities.
 
As of June 30, 2025, all of the Company’s available-for-sale marketable securities were due within one year.
 
The Company had no sales of marketable securities during the six-month periods ended June 30, 2025 and 2024, and accordingly no realized gains or losses were recorded. Proceeds from maturities of available-for-sale marketable securities during the six month periods ended June 30, 2025, and 2024 were $21,643 and $15,825, respectively.
 
NOTE 5:-
FAIR VALUE MEASUREMENTS
 
        
Fair value measurements
as of
 
Description
 
Fair Value Hierarchy
 
June 30,
2025
   
June 30,
2024
 
        Unaudited     Unaudited  
Assets:
     
 
       
Cash equivalents:
               
Money market funds
 
Level 1
 
$
3,819
   
$
3,909
 
Marketable securities:
                   
U.S. Treasury
 
Level 2
 
$
28,875
   
$
32,688
 

 

F - 11


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 6:-
COMMITMENTS AND CONTINGENCIES
 
  a.
The Company provided bank guarantees in the amount of $376 in favor of its offices and car leases in Israel.
 
  b.
Under the office of the Israel Innovation Authority of the Israeli Ministry of Industry, Trade and Labor, formerly known as the Office of the Chief Scientist (“IIA”), the Company is not obligated to repay any amounts received from the IIA if it does not generate any income from products which incorporate technologies which were funded by such research program(s).
 
If income is generated from products which incorporate technologies which were funded by a research program, the Company is committed to pay royalties at a rate of between 3% to 5% of future revenue generated from products that incorporate technologies that were funded by such research program(s), up to a maximum of 100% of the amount received, linked to the U.S. dollar (for grants received under programs approved subsequent to January 1, 1999, the maximum amount to be repaid is 100% plus interest at LIBOR until December 31, 2023, and from January 1, 2024, the 12 months Term SOFR interest). For the six-month periods ended June 30, 2025 and 2024, the Company recorded royalties to the IIA as cost of revenue in the consolidated statements of comprehensive loss in the amount of $0 and $278, respectively.
 
As of June 30, 2025, the Company’s aggregate contingent obligations for payments to IIA, based on royalty-bearing participation received or accrued, net of royalties paid or accrued, totaled $10,047.
 
  c.
On June 25, 2012, the Company entered into an Antibodies Discovery Collaboration Agreement (the “Antibodies Discovery Agreement”) with a U.S. antibody technology company (“mAb Technology Company”), providing an established source for fully human mAbs. Under the Antibodies Discovery Agreement, the mAb Technology Company is entitled to certain royalties that could be eliminated upon payment of certain one-time fees (all milestone and royalties payments referred together as “Contingent Fees”). For the six-month periods ended June 30, 2025 and 2024, the Company did not incur Contingent Fees.
 
  d.
Effective as of January 5, 2018, the Company entered into a Commercial License Agreement (“CLA”) with a European cell line development company. Under the agreement the Company is required to pay an annual maintenance fee, certain amounts upon the occurrence of specified milestones events, and 1% royalties on annual net sales with respect to each commercialized product manufactured using the company’s cell line. Royalties due under the CLA are creditable against the annual maintenance fee. In addition, the Company may at any time prior to the occurrence of a specific milestone event buy-out the royalty payment obligations in a single fixed amount. For the six-month periods ended June 30, 2025 and 2024, the Company did not incur milestone payments. We also entered into a CLA in February 2024 with the European cell line development company for GS-0321. Under the agreement the Company is required to pay an annual maintenance fee and certain amounts upon the occurrence of specified milestones events.

 

F - 12


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 6:-
COMMITMENTS AND CONTINGENCIES (Cont.)
   
  e.
Effective as of October 28, 2020, the Company entered into a collaboration agreement with a U.S. antibody discovery and optimization company for generation and optimization of therapeutic antibodies for the Company. Under the agreement, the Company is required to pay service fees per services performed and certain amounts upon the occurrence of specified milestones events, and single-digit percent royalties on annual net sales with respect to each product sold that comprises or contains one or more antibodies so generated or optimized. The royalty rate is dependent upon the product type and any third-party contribution. For the six-month periods ended June 30, 2025 and 2024 the Company incur in the research and development expenses a milestone payment in the amounts of $750 and $0, respectively.

 

NOTE 7:-
SHAREHOLDERS' EQUITY
 
  a.
Issuance of Shares:
 
On January 31, 2023, the Company entered into a Sales Agreement with Leerink Partners LLC (previously known as SVB Securities LLC) (“Leerink Partners”), as sales agent, pursuant to which the Company may offer and sell, from time to time through Leerink Partners, its ordinary shares through an “at the market offering” (ATM). The offer and sale of our ordinary shares, if any, will be made pursuant to the Company’s shelf registration statement on Form F-3, as supplemented by a prospectus supplement. Pursuant to the applicable prospectus supplement, the Company may offer and sell up to $50,000 of its ordinary shares. As of June 30, 2025, 6,867,191 shares were issued and sold through the ATM, with proceeds of approximately $12,495 (net of $822 issuance expenses).
 
  b.
Share option plan:
 
Transactions related to the grant of options to employees, directors and non-employees under the Company’s 2010 Share Option Plan, as amended, during the six-month period ended June 30, 2025, were as follows:
 
   
Number of options
   
Weighted average
exercise
price
   
Weighted average remaining
contractual life
   
Aggregate intrinsic
value
 
         
$
   
Years
   
$
 
                         
Options outstanding at the beginning of year
   
8,655,721
     
4.31
     
6.05
     
802
 
Options granted
   
31,600
     
1.79
                 
Options exercised
   
(32,470
)
   
1.07
             
24
 
Options forfeited
   
(205,003
)
   
4.66
                 
Options expired
   
(101,648
)
   
6.55
                 
                                 
Options outstanding as of June 30, 2025
   
8,348,200
     
4.28
     
5.54
     
1,263
 
                                 
Exercisable of June 30, 2025
   
6,111,177
     
5.18
     
4.51
     
555
 

 

F - 13


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 7:-
SHAREHOLDERS’ EQUITY (Cont.)

 

During the six-month period ended June 30, 2025, the Company’s Board of Directors granted 31,600 options to purchase ordinary shares of the Company to employees. The exercise prices for such options range from $1.32 to $2.25 per share, with vesting to occur in up to four years.
 
The Company selected the Black-Scholes-Merton (“Black-Scholes”) option-pricing model as the most appropriate fair value method for its share-options awards and Employee Share Purchase Plan (“ESPP”), which is currently suspended. The option-pricing model requires a number of assumptions, of which the most significant are the expected share price volatility and the expected option term. Expected volatility was calculated based on actual historical share price movements over a term that is equivalent to the expected term of granted options. The expected term of options granted is based on historical experience and represents the period of time that options granted are expected to be outstanding.
 
The following table presents the assumptions used to estimate the fair value of the options granted in the periods presented:
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
             
Volatility
   
90.6%-91.0
%
   
92.7%-95.9
%
Risk-free interest rate
   
4.07%-4.37
%
   
3.9%-4.5
%
Dividend yield
   
0
%
   
0
%
Expected life (years)
   
4.14
     
4.02
 
 
Weighted average fair value of options granted during the six-month periods ended June 30, 2025 and 2024 were $1.20 and $1.41, respectively.
 
  c.
RSUs
 
A summary of RSUs activity During the six-month period ended June 30, 2025 is as follows:
 
   
Number of RSUs
   
Weighted average
grant date per value
 
         
$
 
             
RSUs outstanding at the beginning of year
   
317,350
     
1.70
 
RSUs granted
   
23,700
     
1.79
 
RSUs forfeited
   
(15,300
)
   
1.69
 
                 
RSUs outstanding as of June 30, 2025
   
325,750
     
1.70
 

 

F - 14


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 7:-
SHAREHOLDERS’ EQUITY (Cont.)

 

During the six-month periods ended June 30, 2025 and 2024, the Company recorded share-based compensation related to share options and RSUs in a total amount of $987 and $1,633, respectively.
 
As of June 30, 2025, the total unrecognized estimated compensation cost related to non-vested share options and RSUs granted prior to that date was $2,586 which is expected to be recognized over a weighted average period of approximately 2.42 years.
 
The stock-based compensation expenses related to share options and RSU's are included as follows in the expense categories:
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
             
Research and development expenses
 
$
454
   
$
805
 
Marketing and business development expenses
   
52
     
43
 
General and administrative expenses
   
481
     
785
 
                 
Total operating expense
 
$
987
   
$
1,633
 
 
NOTE 8:-
FINANCIAL AND OTHER INCOME, NET
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
             
Interest income
 
$
2,048
   
$
1,770
 
Amortization of discount on marketable securities, net
   
310
     
796
 
Exchange rate differences and other
   
(43
)
   
(38
)
                 
Financial and other income, net
 
$
2,315
   
$
2,528
 

 

F - 15


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 9:-
SEGMENTS, GEOGRAPHIC INFORMATION AND MAJOR CUSTOMER DATA
 
The following table presents selected financial information with respect to the Company’s single operating segment and includes information about segment revenues and significant segment expenses, for the six months ended June 30, 2025 and 2024:
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
   
$
   
$
 
Total Revenues
   
3,541
     
9,261
 
                 
Less:
               
          R&D expenses
               
               Preclinical
   
6,659
     
8,546
 
               Clinical
   
6,982
     
7,107
 
           SG&A
   
4,851
     
4,592
 
           Financial income, net
   
(2,314
)
   
(2,528
)
           Taxes on income
   
14
     
14
 
           Other segment expenses*
   
1,872
     
920
 
                 
Net loss
   
(14,523
)
   
(9,390
)
 
*Other segment expense (income) during the six months ended June 30, 2025 and 2024 includes property and equipment depreciation, GS-0321 asset of set-up activities, share-based compensation and other adjustments.
 
Operations in Israel include research and development, clinical operations, general and administrative, marketing and business development, and operations in the United States include clinical operations. Total revenues are attributed to geographic areas based on the location of the end customer.
 
The following represents the total revenue for the six-month periods ended June 30, 2025 and 2024 by region based on the invoicing address of customers:
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
Revenue from sales to customers:
           
             
United States
 
$
3,541
   
$
4,261
 
Europe
   
-
     
5,000
 
                 
Total revenues
 
$
3,541
   
$
9,261
 

 

F - 16


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 9:-
SEGMENTS, GEOGRAPHIC INFORMATION AND MAJOR CUSTOMER DATA (Cont.)

 

Contract Balances
 
Of the $43,677 and $36,541 of the deferred revenue recorded as of December 31, 2024 and 2023, respectively, the Company recognized $3,541 and $4,261 as revenue during the six months periods ended June 30, 2025 and 2024, respectively.
 
Remaining Performance Obligation
 
The Company’s remaining performance obligations are comprised of revenue not yet recognized. As of June 30, 2025, the aggregate amount of the transaction price allocated to remaining performance obligations was $40,137 that the Company expects to recognize as revenue. As of June 30, 2025, the Company expects to recognize 26% of its remaining performance obligations as revenue over the next 12 months.

 

NOTE 10:-
RELATED PARTY BALANCES AND TRANSACTIONS
 
Balances with related parties:
 
   
June 30,
2025
   
December 31,
2024
 
   
Unaudited
       
             
Trade and other payables (a)
 
$
32
   
$
58
 
 
Related parties' expenses:
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
Amounts charged to:
           
             
Research and development expenses (a)
 
$
60
   
$
74
 
 
  (a)
The Company incurred expenses for research and development services provided by related party for cancer studies in animal models, and breeding and maintenance of animals (mice) to support such studies.

 

F - 17


COMPUGEN LTD. AND ITS SUBSIDIARY

 

NOTES TO INTERIM CONSOLIDATED FINANCIAL STATEMENTS


U.S. dollars in thousands (except share and per share data)

 

NOTE 11:-
LOSSES PER SHARE
 
For the six months ended June 30, 2025 and 2024, the total weighted average number of shares related to outstanding options and RSUs excluded from the calculations of diluted net loss per share were 8,797,858 and 8,002,799, respectively.
 
The following table sets forth the computation of basic and diluted losses per share for the six-month periods ended June 30, 2025 and 2024:
 
   
Six months ended
June 30,
 
   
2025
   
2024
 
   
Unaudited
 
Numerator:
           
             
Net loss for basic and diluted loss per share
 
$
14,523
   
$
9,390
 
                 
Denominator:
               
                 
Weighted average number of ordinary shares
               
used in computing basic and diluted net loss per share
   
92,917,554
     
89,518,778
 
                 
Basic and diluted loss per ordinary share
 
$
(0.16
)
 
$
(0.10
)

 

NOTE 12:-
SUBSEQUENT EVENTS
 
On August 5, 2025, following recommendation of the compensation committee, the Company’s board of directors increased the total number of shares reserved for issuance under the Company’s 2010 Plan by 200,000.

 

F - 18