v3.25.2
COLLABORATION AND LICENSE AGREEMENTS (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Jan. 31, 2024
USD ($)
performance_obligation
Sep. 30, 2021
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue     $ 114,449,000 $ 54,116,000 $ 196,180,000 $ 95,490,000  
License and collaboration revenue              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue     19,607,000 1,940,000 25,478,000 3,330,000  
Vifor Pharma | License and collaboration revenue              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue     19,600,000 $ 1,900,000 25,500,000 $ 3,300,000  
Vifor Pharma | License and Collaboration - Regulatory Milestone              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue     17,500,000   17,500,000    
Vifor Pharma | License and Collaboration - Clinical Development Activities              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue     1,500,000   2,900,000    
Vifor Pharma | License and Collaboration - Sale of Pharmaceutical Ingredients              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue         3,800,000    
Vifor Pharma | Royalty              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue     600,000   1,300,000    
Collaborative Arrangement | Vifor Pharma              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Upfront payment   $ 55,000,000          
Maximum milestone payments from collaborator   $ 845,000,000          
Percentage of royalty on net sales receives up to   40.00%          
Deferred revenue     $ 0   $ 0   $ 2,800,000
Collaborative Arrangement | Vifor Pharma | Regulatory and Market Access Milestone              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Maximum milestone payments from collaborator   $ 135,000,000          
Collaborative Arrangement | Vifor Pharma | Sales-based Milestone Payments              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Maximum milestone payments from collaborator   $ 655,000,000          
Collaborative Arrangement | Renalys Pharma Inc              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Revenue $ 8,300,000            
Force majeure event period threshold 9 months            
Number of performance obligations | performance_obligation 1            
Collaborative Arrangement | Renalys Pharma Inc | Regulatory Development And Sales Based Milestone              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Maximum milestone payments from collaborator $ 120,000,000