v3.25.2
Segment Information - Operating Segment Information (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]            
Collaboration revenue $ 1,950   $ 94,694   $ 22,508 $ 153,814
Total research and development expenses 37,877   32,035   69,951 60,643
General and administrative expenses 10,922   9,236   21,196 18,635
Interest and other income 3,924   4,366   8,365 8,580
Provision for income taxes 178   2,758   178 4,589
Net (loss) income (43,103) $ (17,349) 55,031 $ 23,496 (60,452) 78,527
Reportable Segment            
Segment Reporting Information [Line Items]            
Collaboration revenue 1,950   94,694   22,508 153,814
Total research and development expenses 37,877   32,035   69,951 60,643
General and administrative expenses 10,922   9,236   21,196 18,635
Interest and other income 3,924   4,366   8,365 8,580
Provision for income taxes 178   2,758   178 4,589
Net (loss) income (43,103)   55,031   (60,452) 78,527
Reportable Segment | ENTR-601-44            
Segment Reporting Information [Line Items]            
Total research and development expenses 6,158   2,232   10,892 5,511
Reportable Segment | ENTR-601-45            
Segment Reporting Information [Line Items]            
Total research and development expenses 4,576   588   7,435 3,126
Reportable Segment | ENTR-601-50            
Segment Reporting Information [Line Items]            
Total research and development expenses 2,040   3,216   2,732 5,859
Reportable Segment | ENTR-601-51            
Segment Reporting Information [Line Items]            
Total research and development expenses 2,855   46   3,681 116
Reportable Segment | Collaboration services            
Segment Reporting Information [Line Items]            
Total research and development expenses 527   6,631   1,403 7,384
Reportable Segment | Other preclinical and discovery            
Segment Reporting Information [Line Items]            
Total research and development expenses 1,224   2,028   2,481 3,939
Reportable Segment | Personnel related (including stock-based compensation)            
Segment Reporting Information [Line Items]            
Total research and development expenses 13,231   9,912   25,987 19,812
Reportable Segment | Facility related and other            
Segment Reporting Information [Line Items]            
Total research and development expenses $ 7,266   $ 7,382   $ 15,340 $ 14,896