Collaboration agreement termination description.

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- Definition

Commercial milestone payments.

+ References

No definition available.

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- Definition

Development and regulatory milestone payments.

+ References

No definition available.

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- Definition

Fund received upon completion of certain development milestone.

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No definition available.

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- Definition

Funds provided for pre-clinical research and development activities.

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No definition available.

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- Definition

Maximum repayment amount agreed to pay.

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No definition available.

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- Definition

Milestone Payments

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No definition available.

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- Definition

Milestones achieved.

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No definition available.

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- Definition

Payments for execution of agreement.

+ References

No definition available.

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- Definition

Related party transaction obligation with related party.

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No definition available.

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- Definition

Research agreement expiry date.

+ References

No definition available.

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- Definition

Research and collaboration agreement payments.

+ References

No definition available.

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- Definition

Research And Collaboration Agreement Quarterly Payments

+ References

No definition available.

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- Definition

Carrying value as of the balance sheet date of obligations incurred through that date and payable for royalties.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity.

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Strategic License and Research and Collaboration Agreements - Additional Information (Details) £ in Millions	1 Months Ended						3 Months Ended		6 Months Ended
	Jan. 31, 2025 USD ($)	May 31, 2024 USD ($)	Mar. 31, 2024 USD ($)	Oct. 31, 2023 USD ($)	Feb. 28, 2022 USD ($)	Nov. 30, 2015 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2024 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2025 GBP (£)	Jun. 30, 2024 USD ($)	May 01, 2025 USD ($)	Dec. 31, 2024 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expenses							$ 38,724,000	$ 48,628,000	$ 90,875,000		$ 94,385,000
Fund received upon completion of certain development milestone	$ 1,500,000
2015 TSRI License Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones achieved							0		0
Milestone Payments				$ 300,000
Accrued Royalties							0		$ 0
2015 TSRI License Agreement \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Development and regulatory milestone payments						$ 1,500,000
Commercial milestone payments						$ 3,500,000
Amgen Research and Collaboration Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration agreement termination description									The Amgen Collaboration Agreement automatically terminated upon its third anniversary in September 2024.	The Amgen Collaboration Agreement automatically terminated upon its third anniversary in September 2024.
Related party transaction obligation with related party							0		$ 0			$ 6,300,000	$ 6,300,000
Research and development expenses							0	0	$ 6,300,000		0
Vanderbilt Research Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research agreement expiry date									2023-09	2023-09
First Vanderbilt Research Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and collaboration agreement quarterly payments					$ 1,700,000
Second Vanderbilt Research Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research agreement expiry date									2025-03	2025-03
Second Vanderbilt Research Agreement \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and collaboration agreement payments		$ 600,000
Parkinson's Research Ventures Funding Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expenses							$ 1,100,000	$ 200,000	$ 1,200,000		$ 200,000
Payments for execution of agreement			$ 1,100,000
Maximum repayment amount agreed to pay. \| £										£ 8.4
Parkinson's Research Ventures Funding Agreement \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Funds provided for preclinical research and development activities									$ 2,600,000