v3.25.2
Acquisitions of Assets - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jul. 31, 2025
USD ($)
Dec. 31, 2023
USD ($)
shares
Nov. 30, 2023
USD ($)
Feb. 28, 2022
USD ($)
Sep. 30, 2021
USD ($)
Agreements
shares
Jun. 30, 2020
USD ($)
Dec. 31, 2023
USD ($)
Jun. 30, 2025
USD ($)
Milestones
Dec. 31, 2023
USD ($)
Amgen Inc.                  
Business Combination [Line Items]                  
Number of license agreements | Agreements         2        
Vanderbilt IPR&D Assets                  
Business Combination [Line Items]                  
Contingent consideration deemed due or payable               $ 0  
BlackThorn Merger Agreement                  
Business Combination [Line Items]                  
Contingent consideration, milestone payment settled in cash           $ 10,000,000      
Number of milestone achieved | Milestones               0  
BlackThorn Merger Agreement | BlackThorn Therapeutics, Inc.                  
Business Combination [Line Items]                  
Contingent consideration deemed due or payable               $ 0  
Contingent consideration payable in cash   $ 2,300,000              
Acquired in-process research and developed expense             $ 60,800,000    
BlackThorn Merger Agreement | BlackThorn Therapeutics, Inc. | Common Stock                  
Business Combination [Line Items]                  
Shares issued based on volume weighted average price per share prior to date milestone was met | shares   6,072,445              
BlackThorn Merger Agreement | navacaprant                  
Business Combination [Line Items]                  
Milestone payment due description               milestone payment that became due in October 2023 upon dosing the first patient in the Phase 3 clinical trial for navacaprant,  
BlackThorn Merger Agreement | navacaprant | Maximum | Development and Regulatory Approval Milestones                  
Business Combination [Line Items]                  
Contingent consideration           365,000,000      
BlackThorn Merger Agreement | navacaprant | Maximum | Sales-based Milestones                  
Business Combination [Line Items]                  
Contingent consideration           450,000,000      
BlackThorn Merger Agreement | NMRA-511 | Maximum | Development and Regulatory Approval Milestones                  
Business Combination [Line Items]                  
Contingent consideration           100,000,000      
BlackThorn Merger Agreement | NMRA-511 | Maximum | Sales-based Milestones                  
Business Combination [Line Items]                  
Contingent consideration           $ 100,000,000      
BlackThorn Carveout Plan                  
Business Combination [Line Items]                  
Number of milestone achieved | Milestones               0  
Contingent consideration deemed due or payable               $ 0  
Asset acquisition compensation recognized and paid                 $ 1,800,000
Amgen Inc. Licenses | Amgen Inc.                  
Business Combination [Line Items]                  
Number of milestone achieved | Milestones               0  
Contingent consideration deemed due or payable               $ 0  
Amgen Inc. Licenses | Amgen Inc. | Series A-2                  
Business Combination [Line Items]                  
Upfront consideration transferred shares | shares         20,000,000        
Acquisition date fair value of shares transferred         $ 57,000,000        
Amgen Inc. Licenses | Amgen Inc. | Maximum | Case One                  
Business Combination [Line Items]                  
Contingent consideration payable in cash         360,000,000        
Amgen Inc. Licenses | Amgen Inc. | Maximum | Commercial Milestone Payment | Case Two                  
Business Combination [Line Items]                  
Contingent consideration payable in cash         $ 360,000,000        
Vanderbilt License                  
Business Combination [Line Items]                  
Contingent consideration, milestone payment settled in cash     $ 2,000,000            
Number of milestone achieved | Milestones               0  
Acquired in-process research and development             $ 800,000    
Vanderbilt License | Maximum | Achievement of Specified Development Events                  
Business Combination [Line Items]                  
Contingent consideration payable in cash       $ 42,400,000          
Vanderbilt License | Maximum | Achievement of Specified Commercialization Events                  
Business Combination [Line Items]                  
Contingent consideration payable in cash       380,000,000          
Vanderbilt License | Subsequent Event                  
Business Combination [Line Items]                  
Contingent consideration, milestone payment settled in cash $ 5,000,000                
Vanderbilt License | Vanderbilt IPR&D Assets                  
Business Combination [Line Items]                  
Upfront cash payment       $ 13,000,000