v3.25.2
Document And Entity Information
Aug. 06, 2025
Cover [Abstract]  
Document Type 8-K
Amendment Flag false
Document Period End Date Aug. 06, 2025
Entity Registrant Name UPSTREAM BIO, INC.
Entity Central Index Key 0002022626
Entity Emerging Growth Company true
Entity File Number 001-42366
Entity Incorporation, State or Country Code DE
Entity Tax Identification Number 38-4187694
Entity Address, Address Line One 890 Winter Street
Entity Address, Address Line Two Suite 200
Entity Address, City or Town Waltham
Entity Address, State or Province MA
Entity Address, Postal Zip Code 02451
City Area Code (781)
Local Phone Number 208-2466
Entity Information, Former Legal or Registered Name Not Applicable
Written Communications false
Soliciting Material false
Pre-commencement Tender Offer false
Pre-commencement Issuer Tender Offer false
Entity Ex Transition Period false
Title of 12(b) Security Common Stock, $0.001 par value per share
Trading Symbol UPB
Security Exchange Name NASDAQ