S-1 S-1/A EX-FILING FEES 333-288733 0001464521 Heartflow, Inc. N/A Y Y N N 0001464521 2025-08-06 2025-08-06 0001464521 1 2025-08-06 2025-08-06 0001464521 1 2025-08-06 2025-08-06 0001464521 2 2025-08-06 2025-08-06 0001464521 3 2025-08-06 2025-08-06 0001464521 4 2025-08-06 2025-08-06 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-1

Heartflow, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Common stock, $0.001 par value per share 457(a) 19,166,667 $ 18.00 $ 345,000,006.00 0.0001531 $ 52,819.50
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 345,000,006.00

$ 52,819.50

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 37,413.81

Net Fee Due:

$ 15,405.69

Offering Note

1

1a. Includes 2,500,000 shares that the underwriters have the option to purchase, if any. 1b. Estimated solely for the purpose of computing the amount of the registration fee pursuant to Rule 457(a) under the Securities Act of 1933, as amended.

Table 2: Fee Offset Claims and Sources ☐Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims 1 S-1 333-288733 07/17/2025 $ 15,310.00
Fee Offset Claims 2 S-1 333-288733 07/17/2025 $ 22,103.81
Fee Offset Sources Heartflow, Inc. S-1 333-288733 07/17/2025 $ 15,310.00
Fee Offset Sources Heartflow, Inc. S-1 333-288733 08/01/2025 $ 22,103.81
Rule 457(p)
Fee Offset Claims
Fee Offset Sources

Explanation of the basis for claimed offset:

1

1a. The Registrant previously paid registration fees of (a) $15,310.00 in connection with the initial filing of this Registration Statement on Form S-1 on July 17, 2025 and (b) $22,103.81 in connection with the filing of Amendment No. 1 to this Registration Statement on Form S-1 on August 1, 2025.

2

See note 1a.

Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A