Net Loss Per Common Share - Schedule of Earnings Per Share, Basic and Diluted (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Numerator:
Net loss attributable to Zentalis	$ (26,874)	$ (88,277)	$ (75,153)	$ (78,209)
Denominator:
Weighted average number of common shares outstanding, basic (in shares)	71,992,000	71,040,000	71,836,000	70,969,000
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Weighted average number of common shares outstanding, diluted (in shares)	71,992,000	71,040,000	71,836,000	70,969,000
Earnings Per Share, Basic And Diluted EPS [Abstract]
Basic (in dollars per share)	$ (0.37)	$ (1.24)	$ (1.05)	$ (1.10)
Diluted (in dollars per share)	$ (0.37)	$ (1.24)	$ (1.05)	$ (1.10)

The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.

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+ Details

- Definition

The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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+ Details