v3.25.2
Cover - shares
 6 Months Ended
Jun. 30, 2025
Aug. 01, 2025
Cover [Abstract]    
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Jun. 30, 2025  
Document Transition Report false  
Entity File Number 001-39263  
Entity Registrant Name Zentalis Pharmaceuticals, Inc.  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 82-3607803  
Entity Address, Address Line One 10275 Science Center Dr.  
Entity Address, Address Line Two Suite 200  
Entity Address, City or Town San Diego  
Entity Address, State or Province CA  
Entity Address, Postal Zip Code 92121  
City Area Code 858  
Local Phone Number 263-4333  
Title of 12(b) Security Common Stock,$0.001 par value per share  
Trading Symbol ZNTL  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   72,135,453
Entity Central Index Key 0001725160  
Amendment Flag false  
Document Fiscal Period Focus Q2  
Current Fiscal Year End Date --12-31  
Document Fiscal Year Focus 2025