v3.25.2
Segment Reporting - Schedule of reportable segment net income (loss) (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]            
Operating Expenses $ 24,881   $ 28,871   $ 52,117 $ 63,309
Gain on sale of VOWST Business (185)   0   (52,366) 0
Net income (loss) from continuing operations (19,855)   (26,196)   12,827 (59,099)
Net (loss) from discontinuing operations, net of tax 0   (6,674)   0 (13,904)
Net income (loss) (19,855) $ 32,682 (32,870) $ (40,133) 12,827 (73,003)
Operating Segments [Member]            
Segment Reporting Information [Line Items]            
R&D personnel-related (including stock-based compensation) 6,084   6,906   12,202 14,751
G&A personnel-related (including stock-based compensation) 3,725   5,698   7,898 12,339
Professional fees 2,155   2,091   5,335 4,719
Facility-related and other 4,373   5,276   8,908 10,951
Gain on sale of VOWST Business (185)   0   (52,366) 0
Other segment expense (income) [1] (3,149)   (2,669)   (7,356) (4,119)
Net income (loss) from continuing operations (19,855)   (26,196)   12,827 (59,099)
Net (loss) from discontinuing operations, net of tax [2] 0   (6,674)   0 (13,904)
Net income (loss) (19,855)   (32,870)   12,827 (73,003)
Live Biotherapeutics Platform [Member] | Operating Segments [Member]            
Segment Reporting Information [Line Items]            
Operating Expenses 5,808   6,687   10,931 15,851
SER-155 [Member] | Operating Segments [Member]            
Segment Reporting Information [Line Items]            
Operating Expenses $ 1,044   $ 2,207   $ 1,621 $ 4,607
[1]

[1] Other segment (expense) income includes manufacturing services expenses, research and development expenses on early stage programs, interest income and other (expense) income, net.

[2] See Note 3, Discontinued Operations and TSA, for further details.