| Schedule of Segment Reporting Information, by Segment [Table Text Block] |
| |
|
Three Months Ended |
|
|
Six Months Ended |
|
| |
|
June 30, |
|
|
June 30, |
|
| |
|
2025 |
|
|
2024 |
|
|
2025 |
|
|
2024 |
|
| Significant and other segment expenses |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Research and development |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PIPE-791 |
|
$ |
6,178 |
|
|
$ |
2,028 |
|
|
$ |
11,732 |
|
|
$ |
4,889 |
|
| PIPE-307 |
|
|
2,160 |
|
|
|
2,258 |
|
|
|
4,775 |
|
|
|
4,333 |
|
| CTX-343 |
|
|
1,059 |
|
|
|
574 |
|
|
|
2,437 |
|
|
|
886 |
|
| Discovery programs |
|
|
1,328 |
|
|
|
1,244 |
|
|
|
2,710 |
|
|
|
2,348 |
|
| Unallocated internal costs(1) |
|
|
3,338 |
|
|
|
1,797 |
|
|
|
6,121 |
|
|
|
3,223 |
|
| General and administrative |
|
|
3,839 |
|
|
|
3,043 |
|
|
|
8,237 |
|
|
|
5,195 |
|
| Interest income |
|
|
2,029 |
|
|
|
2,001 |
|
|
|
4,279 |
|
|
|
3,637 |
|
| Other segment items(2) |
|
|
(167 |
) |
|
|
(66 |
) |
|
|
(297 |
) |
|
|
(189 |
) |
| Net loss |
|
$ |
(16,040 |
) |
|
$ |
(9,009 |
) |
|
$ |
(32,030 |
) |
|
$ |
(17,426 |
) |
|