Segment Data - Schedule of Reportable Segment Net Revenues and Loss (Details) - USD ($) |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2024 |
Mar. 31, 2024 |
Jun. 30, 2025 |
Jun. 30, 2024 |
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| Segment Reporting Information [Line Items] | ||||||
| License and collaboration revenue | $ 8,466,000 | $ 11,772,000 | $ 15,936,000 | $ 19,182,000 | ||
| Research and development expenses | 101,758,000 | 87,041,000 | 200,574,000 | 171,859,000 | ||
| General and administrative expenses | 26,859,000 | 29,626,000 | 54,799,000 | 56,350,000 | ||
| Facility and information technology related expenses | 14,576,000 | 14,210,000 | 28,960,000 | 27,877,000 | ||
| Depreciation and amortization | 5,538,000 | 5,576,000 | 11,066,000 | 11,007,000 | ||
| Stock-based compensation | 24,367,000 | 31,604,000 | 51,049,000 | 60,885,000 | ||
| Interest and other income | (12,326,000) | (14,190,000) | (22,190,000) | (26,039,000) | ||
| Income tax expense | 39,000 | 0 | 39,000 | |||
| Other segment items | (5,206,000) | 2,588,000 | (4,673,000) | 8,550,000 | ||
| Net loss | (102,291,000) | $ (109,270,000) | (91,051,000) | $ (98,669,000) | (211,561,000) | (189,720,000) |
| External Research And Development Expenses [Member] | ||||||
| Segment Reporting Information [Line Items] | ||||||
| Research and development expenses | 39,891,000 | 24,206,000 | 74,312,000 | 49,567,000 | ||
| External General And Administrative Expenses [Member] | ||||||
| Segment Reporting Information [Line Items] | ||||||
| General and administrative expenses | 6,302,000 | 7,630,000 | 11,675,000 | 12,696,000 | ||
| Employee Related Expenses [Member] | ||||||
| Segment Reporting Information [Line Items] | ||||||
| Research and development expenses | 27,623,000 | 23,026,000 | 56,865,000 | 47,595,000 | ||
| General and administrative expenses | $ 9,992,000 | $ 8,134,000 | $ 20,433,000 | $ 16,725,000 | ||
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- Definition Amount of expense related to facilities and information technology. No definition available.
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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The current period expense charged against earnings on long-lived, physical assets not used in production, and which are not intended for resale, to allocate or recognize the cost of such assets over their useful lives; or to record the reduction in book value of an intangible asset over the benefit period of such asset; or to reflect consumption during the period of an asset that is not used in production. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The amount of interest income and other income recognized during the period. Included in this element is interest derived from investments in debt securities, cash and cash equivalents, and other investments which reflect the time value of money or transactions in which the payments are for the use or forbearance of money and other income from ancillary business-related activities (that is, excluding major activities considered part of the normal operations of the business). No definition available.
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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- Definition Amount of other expense (income) and loss (gain) calculated as difference between segment revenue and separately disclosed expense category to arrive at segment profit (loss). Reference 1: http://www.xbrl.org/2003/role/exampleRef
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