v3.25.2
Document and Entity Information - shares
 6 Months Ended
Jun. 30, 2025
Jul. 28, 2025
Cover [Abstract]    
Document Type 10-Q  
Amendment Flag false  
Document Period End Date Jun. 30, 2025  
Document Fiscal Year Focus 2025  
Document Fiscal Period Focus Q2  
Current Fiscal Year End Date --12-31  
Document Quarterly Report true  
Document Transition Report false  
Entity File Number 001-41837  
Entity Registrant Name Mural Oncology plc  
Entity Central Index Key 0001971543  
Entity Incorporation, State or Country Code L2  
Entity Tax Identification Number 98-1748617  
Entity Address, Address Line One 10 Earlsfort Terrace  
Entity Address, City or Town Dublin 2  
Entity Address, Country IE  
Entity Address, Postal Zip Code D02 T380  
City Area Code 353  
Local Phone Number 1-905-8020  
Title of 12(b) Security Ordinary shares, nominal value $0.01 per share  
Trading Symbol MURA  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company true  
Entity Ex Transition Period false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   17,324,359