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Collaborative Arrangement, Expected Development Cost Funds, Year Two

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Collaborative Arrangements, Investments In Counterparty

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Total upfront and milestone payments made to collaborative partner.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 808
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479402/808-10-50-1

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Collaborative and Other Relationships - Other Research and Discovery Arrangements and Funding Arrangements (Details) - USD ($) $ in Millions	3 Months Ended	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2025	Feb. 11, 2025
Collaborative arrangements and non-collaborative arrangement transactions
Reduction of research and development expense	$ 50.0	$ 100.0
Milestone Payment, Future Development
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	250.0	250.0
Felzartamab And Izastobart/HIB210 \| Human Immunology Biosciences Pre-Existing In License Commitments \| Milestone Payment, One
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	35.0	35.0
Felzartamab And Izastobart/HIB210 \| Human Immunology Biosciences Pre-Existing In License Commitments \| Milestone Payment, Two
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	30.0	30.0
Felzartamab And Izastobart/HIB210 \| Human Immunology Biosciences Pre-Existing In License Commitments \| Milestone Payment, Future Development
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	130.0	130.0
Felzartamab And Izastobart/HIB210 \| Human Immunology Biosciences Pre-Existing In License Commitments \| Milestone Payment, Regulatory
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	230.0	230.0
Felzartamab And Izastobart/HIB210 \| Human Immunology Biosciences Pre-Existing In License Commitments \| Milestone Payment, Commercial
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	640.0	640.0
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative arrangements and non-collaborative arrangement transactions
Expected receipts to co-fund development costs, current			$ 200.0
Expected receipts to co-fund development costs, noncurrent			$ 50.0
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| City Therapeutics, Inc.
Collaborative arrangements and non-collaborative arrangement transactions
Upfront and milestone paymentsmade to collaborative partner	16.0	16.0
Collaborative arrangements, investments in counterparty	30.0	30.0
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| Milestone Payment, Research \| City Therapeutics, Inc.
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	21.5	21.5
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| Milestone Payment, Developmental \| City Therapeutics, Inc.
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	360.0	360.0
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| Milestone Payment, Sales-Based \| City Therapeutics, Inc.
Collaborative arrangements and non-collaborative arrangement transactions
Estimated additional payments upon achievement of development and commercial milestones	$ 625.0	$ 625.0