v3.25.2
REVENUE - Disaggregation of Revenue by Product and Region (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Revenue from External Customer [Line Items]        
Total Revenues $ 12,269 $ 12,201 $ 23,470 $ 24,066
Performance obligation satisfied in previous period 230 76 674 258
United States        
Revenue from External Customer [Line Items]        
Total Revenues 8,519 8,801 16,392 17,277
International        
Revenue from External Customer [Line Items]        
Total Revenues 3,481 3,224 6,590 6,414
Other        
Revenue from External Customer [Line Items]        
Total Revenues 270 176 488 375
Growth Portfolio        
Revenue from External Customer [Line Items]        
Total Revenues 6,596 5,596 12,159 10,388
Opdivo        
Revenue from External Customer [Line Items]        
Total Revenues 2,560 2,387 4,824 4,465
Opdivo Qvantig        
Revenue from External Customer [Line Items]        
Total Revenues 30 0 38 0
Orencia        
Revenue from External Customer [Line Items]        
Total Revenues 963 948 1,733 1,746
Yervoy        
Revenue from External Customer [Line Items]        
Total Revenues 728 630 1,351 1,213
Reblozyl        
Revenue from External Customer [Line Items]        
Total Revenues 568 425 1,046 779
Opdualag        
Revenue from External Customer [Line Items]        
Total Revenues 284 235 537 441
Breyanzi        
Revenue from External Customer [Line Items]        
Total Revenues 344 153 607 260
Camzyos        
Revenue from External Customer [Line Items]        
Total Revenues 260 139 419 223
Zeposia        
Revenue from External Customer [Line Items]        
Total Revenues 150 151 257 261
Abecma        
Revenue from External Customer [Line Items]        
Total Revenues 87 95 190 177
Sotyktu        
Revenue from External Customer [Line Items]        
Total Revenues 70 53 126 97
Krazati        
Revenue from External Customer [Line Items]        
Total Revenues 48 32 96 53
Cobenfy        
Revenue from External Customer [Line Items]        
Total Revenues 35 0 62 0
Other Growth products        
Revenue from External Customer [Line Items]        
Total Revenues 470 348 874 673
Legacy Portfolio        
Revenue from External Customer [Line Items]        
Total Revenues 5,673 6,605 11,311 13,678
Eliquis        
Revenue from External Customer [Line Items]        
Total Revenues 3,680 3,416 7,245 7,136
Revlimid        
Revenue from External Customer [Line Items]        
Total Revenues 838 1,353 1,774 3,022
Pomalyst/Imnovid        
Revenue from External Customer [Line Items]        
Total Revenues 708 959 1,366 1,824
Sprycel        
Revenue from External Customer [Line Items]        
Total Revenues 120 424 295 798
Abraxane        
Revenue from External Customer [Line Items]        
Total Revenues 105 231 210 448
Other Legacy products        
Revenue from External Customer [Line Items]        
Total Revenues $ 223 $ 222 $ 421 $ 450