Exhibit 15.1

	Onestop Assurance PAC
	10 Anson Road
	#06-15 International Plaza Singapore 079903
	Email: audit@onestop-audit.com Website: www.onestop-audit.com

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in the Registration Statement on Form S-8 (File No. 333-283335) of our report dated July 30, 2025, relating to the audit of the consolidated statements of financial position of Metalpha Technology Holding Limited and related consolidated statement of profit or loss and comprehensive loss, changes in equity, and cash flows of the year ended March 31, 2025 and related notes (collectively referred to as the “financial statements”), which appears in this Form 20-F Commission on July 30, 2025.