Insider Trading Arrangements |
3 Months Ended |
|---|---|
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Jun. 30, 2025
shares
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| Trading Arrangements, by Individual | |
| Material Terms of Trading Arrangement | We describe the material terms of these Rule 10b5-1 Trading Plans below. On May 19, 2025, Paul B. Bolno, M.D., MBA, our President and Chief Executive Officer, adopted a Rule 10b5-1 Trading Plan providing for the sale of up to an aggregate of 2,563,388 of our ordinary shares pursuant to the terms of such Rule 10b5-1 Trading Plan. Dr. Bolno's Rule 10b5-1 Trading Plan is active until , or earlier, if and when all transactions under the Rule 10b5-1 Trading Plan are completed. On May 16, 2025, Chandra Vargeese, Ph.D., our Chief Technology Officer, Head of Platform Discovery Sciences, adopted a Rule 10b5-1 Trading Plan providing for the sale of up to an aggregate of 94,600 of our ordinary shares pursuant to the terms of such Rule 10b5-1 Trading Plan. Dr. Vargeese's Rule 10b5-1 Trading Plan is active until , or earlier, if and when all transactions under the Rule 10b5-1 Trading Plan are completed. Except as disclosed above, none of our directors or executive officers adopted, modified or terminated any contract, instruction or written plan for the purchase or sale of our securities that was intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) or any “non-Rule 10b5-1 trading arrangement” as such term is defined in Item 408(a) of Regulation S-K, during the fiscal quarter ended June 30, 2025. |
| Rule 10b5-1 Arrangement Adopted | false |
| Non-Rule 10b5-1 Arrangement Adopted | false |
| Rule 10b5-1 Arrangement Terminated | false |
| Non-Rule 10b5-1 Arrangement Terminated | false |
| Rule 10b5-1 Arrangement Modified | false |
| Non-Rule 10b5-1 Arrangement Modified | false |
| Trading Arrangement 1 [Member] | Paul B. Bolno [Member] | |
| Trading Arrangements, by Individual | |
| Name | Paul B. Bolno |
| Title | President and Chief Executive Officer |
| Rule 10b5-1 Arrangement Adopted | true |
| Adoption Date | May 19, 2025 |
| Arrangement Duration | 181 days |
| Aggregate Available | 2,563,388 |
| Trading Arrangement 2 [Member] | Chandra Vargeese [Member] | |
| Trading Arrangements, by Individual | |
| Name | Chandra Vargeese |
| Title | Chief Technology Officer |
| Rule 10b5-1 Arrangement Adopted | true |
| Adoption Date | May 16, 2025 |
| Arrangement Duration | 189 days |
| Aggregate Available | 94,600 |