v3.25.2
Segment Information - Schedule of Reconciliation to Consolidated Operating Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]        
Total research and development expenses $ 43,469 $ 40,393 $ 84,091 $ 73,840
General and administrative expenses 17,989 14,296 36,346 27,845
Total operating expenses 61,458 54,689 120,437 101,685
AATD Program [Member]        
Segment Reporting Information [Line Items]        
Total research and development expenses 1,846 3,172 3,292 6,365
INHBE Program [Member]        
Segment Reporting Information [Line Items]        
Total research and development expenses 3,515 1,646 6,054 2,381
DMD Program [Member]        
Segment Reporting Information [Line Items]        
Total research and development expenses 2,681 4,051 5,719 7,101
HD Program [Member]        
Segment Reporting Information [Line Items]        
Total research and development expenses 789 3,636 1,956 6,015
Other Research and Development Expenses, Including RNA Editing, PRISM, Others [Member]        
Segment Reporting Information [Line Items]        
Total research and development expenses $ 34,638 $ 27,888 $ 67,070 $ 51,978