Allocated share based compensation expense to be recognized.

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- Definition

Number of milestones achieved.

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No definition available.

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- Definition

Share based compensation arrangement by share based payment award award cliff vesting period.

+ References

No definition available.

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- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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- Definition

Amount of cost not yet recognized for nonvested award under share-based payment arrangement.

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Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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- Definition

Amount of noncash expense for share-based payment arrangement.

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- Definition

Amount of additional cost recognized for award under share-based payment arrangement from occurrence of event accelerating recognition of cost.

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Estimated period over which an employee is required to provide service in exchange for the equity-based payment award, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date.

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The number of equity-based payment instruments, excluding stock (or unit) options, that vested during the reporting period.

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Fair value of share-based awards for which the grantee gained the right by satisfying service and performance requirements, to receive or retain shares or units, other instruments, or cash.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Number of additional shares authorized for issuance under share-based payment arrangement.

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- Definition

Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

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Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options exercised (or share units converted) into shares.

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Gross number of share options (or share units) granted during the period.

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The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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Number of options outstanding, including both vested and non-vested options.

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The increase or decrease in number of shares reserved for issuance under stock option agreements awarded under the plan that validly exist and are outstanding, including vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Number of shares purchased for issuance under share-based payment arrangement.

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Percentage of vesting of award under share-based payment arrangement.

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Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Stock-Based Compensation - Additional Information (Detail)					3 Months Ended		6 Months Ended
	Jun. 11, 2025 shares	Jun. 10, 2024 shares	Feb. 21, 2024 $ / shares shares	Jun. 15, 2023 shares	Jun. 30, 2025 USD ($) Milestone $ / shares shares	Jun. 30, 2024 USD ($) Milestone shares	Jun. 30, 2025 USD ($) Milestone $ / shares shares	Jun. 30, 2024 USD ($) Milestone $ / shares shares	Dec. 31, 2024 $ / shares shares	Apr. 16, 2024 shares	Jan. 23, 2024 $ / shares	Jun. 16, 2022 shares	Sep. 20, 2018 shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share based compensation granted under plan vested period							4 years
Share based compensation, vest period							1 year
Share based compensation, term of plan							10 years
Stock-based compensation expense tied to total stockholder return \| $							$ 15,660,000	$ 30,865,000
Stock-based compensation expense \| $					$ 8,733,000	$ 17,167,000	$ 15,660,000	$ 30,865,000
Weighted average grant date fair value per share \| $ / shares							$ 4.81	$ 14.69
Time Based Restricted Stock Units [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted stock units granted					82,840	24,941	1,576,292	882,025
Restricted stock units vested					9,430	10,096	1,154,333	80,039
Fair value of restricted stock units vested \| $					$ 100,000	$ 100,000	$ 8,500,000	$ 1,700,000
Outstanding and unvested restricted stock units					1,916,330		1,916,330
Total unrecognized stock-based compensation expense \| $					$ 14,200,000		$ 14,200,000
Weighted average period of unrecognized compensation costs							3 years 4 months 9 days
Performance Restricted Stock Units [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense tied to total stockholder return \| $					$ 500,000	$ 400,000	$ 700,000	$ 800,000
Restricted stock units granted					6,000	0	418,000	395,055
Restricted stock units vested					87,357
Fair value of restricted stock units vested \| $					$ 600,000	$ 0		$ 0
Stock-based compensation expense \| $					2,900,000
Stock-based compensation expense to be recognized \| $					$ 200,000		$ 200,000
Outstanding and unvested restricted stock units					1,174,141		1,174,141
Total unrecognized stock-based compensation expense \| $					$ 30,200,000		$ 30,200,000
Regulatory development Milestone achieved \| Milestone					1
Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options granted							1,086,975
Stock options exercise price per share \| $ / shares					$ 44.94		$ 44.94		$ 52.52
Total number of shares outstanding					5,562,401		5,562,401		5,757,824
Stock-based compensation expense \| $					$ 3,468,000	7,724,000	$ 6,823,000	15,175,000
Total unrecognized stock-based compensation expense \| $					$ 19,500,000		$ 19,500,000
Weighted average period of unrecognized compensation costs							3 years 9 months 3 days
Intrinsic value of options exercised \| $							$ 0	100,000
Exercise price per share of the replacement options \| $ / shares					$ 54.55		$ 54.55
Performance-Based Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense \| $					$ 0	$ 0	$ 0	$ 0
Performance Shares [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options granted					0	0	0	0
Total unrecognized stock-based compensation expense \| $					$ 24,900,000		$ 24,900,000
Number of shares outstanding and unvested stock options					455,000		455,000
Restricted Stock Units Vest One Year Anniversary [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted stock units vesting percentage							25.00%
2011 Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options granted							0
2014 Plan [Member] \| Performance-Based Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Regulatory development Milestone achieved \| Milestone					0	0	0	0
2016 Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total number of shares reserved for issuance										428,074			1,200,000
2014 Employee Stock Purchase Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Additional number of shares reserved for issuance	500,000			500,000
Total number of shares reserved for issuance				1,582,000								300,000
Common stock available for issuance under stock option plan					866,758		866,758
Number of shares issued under the plan							715,242
Option Exchange Program [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options granted			1,483,113
Share based compensation granted under plan vested period			18 months
Share based compensation, term of plan			7 years
Exercise price per share of the replacement options \| $ / shares			$ 22.2
Options to purchase			3,079,608
Additional stock-based compensation expense \| $							$ 1,700,000
Replacement options vesting period							18 months
Option Exchange Program [Member] \| Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock options exercise price per share \| $ / shares											$ 35
2024 Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock shares annual increase added to plan		11,002,166
Total number of shares reserved for issuance		5,500,000
Common stock available for issuance under stock option plan					6,247,443		6,247,443
2024 Plan, 2014 Plan and 2016 Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total number of shares outstanding					8,652,872		8,652,872