The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
MEIRAGTX HLDGS PLC COM G59665102 1,056,240 163,000 SH SOLE 163,000 0 0
NOBLE CORP PLC ORD SHS A G65431127 392,035 14,287 SH SOLE 14,287 0 0
ROIVANT SCIENCES LTD SHS G76279101 1,388,538 126,923 SH SOLE 126,923 0 0
VALARIS LTD CL A G9460G101 605,952 13,803 SH SOLE 13,803 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 2,168,397 44,700 SH SOLE 44,700 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 84,822,350 114,000 SH SOLE 114,000 0 0
UROGEN PHARMA LTD COM M96088105 1,401,238 107,622 SH SOLE 107,622 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 10,045,100 4,997,562 SH SOLE 4,997,562 0 0
UNIQURE NV SHS N90064101 6,260,329 447,486 SH SOLE 447,486 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 883,786 135,550 SH SOLE 135,550 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 220,575 509,059 SH SOLE 509,059 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 3,169,824 148,400 SH SOLE 148,400 0 0
AMAZON COM INC COM 023135106 32,771,500 149,000 SH SOLE 149,000 0 0
AMBEV SA SPONSORED ADR 02319V103 1,925,802 795,786 SH SOLE 795,786 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 4,736,490 344,472 SH SOLE 344,472 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 9,850,523 612,214 SH SOLE 612,214 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 673,585 294,142 SH SOLE 294,142 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 1,309,160 46,000 SH SOLE 46,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 5,429,814 52,732 SH SOLE 52,732 0 0
BIOGEN INC COM 09062X103 2,666,435 20,500 SH SOLE 20,500 0 0
BIONTECH SE SPONSORED ADS 09075V102 1,181,212 10,987 SH SOLE 10,987 0 0
CARVANA CO CL A 146869102 1,684,800 5,000 SH SOLE 5,000 0 0
COINBASE GLOBAL INC COM CL A 19260Q107 24,185,620 70,000 SH SOLE 70,000 0 0
DYNE THERAPEUTICS INC COM 26818M108 239,273 27,566 SH SOLE 27,566 0 0
EMX RTY CORP COM 26873J107 544,590 216,968 SH SOLE 216,968 0 0
FATE THERAPEUTICS INC COM 31189P102 126,643 111,090 SH SOLE 111,090 0 0
4D MOLECULAR THERAPEUTICS IN COM 35104E100 819,451 197,458 SH SOLE 197,458 0 0
HIMS & HERS HEALTH INC COM CL A 433000106 1,096,700 22,000 SH SOLE 22,000 0 0
IONIS PHARMACEUTICALS INC COM 462222100 10,687,705 267,594 SH SOLE 267,594 0 0
KRYSTAL BIOTECH INC COM 501147102 1,295,573 9,320 SH SOLE 9,320 0 0
LEXEO THERAPEUTICS INC COM 52886X107 752,662 178,356 SH SOLE 178,356 0 0
MERCK & CO INC COM 58933Y105 4,834,398 59,093 SH SOLE 59,093 0 0
MODERNA INC COM 60770K107 2,967,493 103,433 SH SOLE 103,433 0 0
NOV INC COM 62955J103 825,278 63,876 SH SOLE 63,876 0 0
NVIDIA CORPORATION COM 67066G104 12,529,860 81,000 SH SOLE 81,000 0 0
PALANTIR TECHNOLOGIES INC CL A 69608A108 46,584,000 350,000 SH SOLE 350,000 0 0
PAN AMERN SILVER CORP COM 697900108 844,815 29,747 SH SOLE 29,747 0 0
PFIZER INC COM 717081103 927,206 37,029 SH SOLE 37,029 0 0
RECURSION PHARMACEUTICALS IN CL A 75629V104 610,470 119,000 SH SOLE 119,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 1,120,848 432,760 SH SOLE 432,760 0 0
SANDRIDGE ENERGY INC COM NEW 80007P869 400,948 37,022 SH SOLE 37,022 0 0
SAREPTA THERAPEUTICS INC COM 803607100 697,774 39,400 SH SOLE 39,400 0 0
SEA LTD SPONSORD ADS 81141R100 32,501,800 210,000 SH SOLE 210,000 0 0
SEABRIDGE GOLD INC COM 811916105 648,329 44,074 SH SOLE 44,074 0 0
SHOPIFY INC CL A SUB VTG SHS 82509L107 48,970,700 430,000 SH SOLE 430,000 0 0
SIBANYE STILLWATER LTD SPONSORED ADR 82575P107 247,811 34,040 SH SOLE 34,040 0 0
SPROTT FDS TR URANIUM MINERS E 85208P303 761,159 16,278 SH SOLE 16,278 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106 315,666 134,900 SH SOLE 134,900 0 0
TESLA INC COM 88160R101 74,670,220 242,000 SH SOLE 242,000 0 0
TIDEWATER INC NEW COM 88642R109 255,195 5,350 SH SOLE 5,350 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 9,184,804 253,304 SH SOLE 253,304 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 3,752,928 8,300 SH SOLE 8,300 0 0
VIZSLA SILVER CORP COM NEW 92859G608 732,307 250,790 SH SOLE 250,790 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 78,752 25,241 SH SOLE 25,241 0 0
ZAI LAB LTD ADR 98887Q104 4,649,087 132,189 SH SOLE 132,189 0 0