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Share-based compensation - Summary of share-based compensation expense and unrecognized costs (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2018	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
2014 Plan
Share-based compensation
Share-based compensation expense			$ 5,084	$ 6,880	$ 9,494	$ 14,071
Unrecognized compensation costs	$ 38,367		$ 38,367		$ 38,367
Weighted-average remaining period for recognition (in years)					2 years 4 months 2 days
Increase in authorized shares	2,400,000
Ordinary shares available for issue	4,484,501		4,484,501		4,484,501
2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			$ 5,084	6,880	$ 9,494	14,071
Cost of manufacturing services revenue \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense				690		1,035
Research and development \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			2,758	2,856	5,221	6,281
Selling, general and administrative \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			2,326	3,334	4,273	6,755
Share options \| 2014 Plan
Share-based compensation
Unrecognized compensation costs	$ 15,146		15,146		$ 15,146
Weighted-average remaining period for recognition (in years)					2 years 8 months 19 days
Share options \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			1,662	2,660	$ 3,299	5,573
Restricted Share Units \| 2014 Plan
Share-based compensation
Unrecognized compensation costs	21,007		21,007		$ 21,007
Weighted-average remaining period for recognition (in years)					2 years 3 months 3 days
Restricted Share Units \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			2,547	4,214	$ 4,760	8,584
Performance Share Units \| 2014 Plan
Share-based compensation
Unrecognized compensation costs	$ 2,214		2,214		$ 2,214
Weighted-average remaining period for recognition (in years)					6 months
Performance Share Units \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			$ 875	$ 3	$ 1,435	$ (96)
Employee Share Purchase Plan \| Employee Share Purchase Plan
Share-based compensation
Ordinary shares available for issue	86,712	150,000	86,712	86,712	86,712	86,712
Discounted rate for purchase of shares		85.00%
Employee Share Purchase Plan \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense				$ 3		$ 10