Alliance Revenue (Details) - USD ($) $ in Millions |
3 Months Ended | 6 Months Ended | ||
|---|---|---|---|---|
Jun. 30, 2025 |
Jun. 30, 2024 |
Jun. 30, 2025 |
Jun. 30, 2024 |
|
| Disclosure of products and services [line items] | ||||
| Alliance revenue | $ 654 | $ 482 | $ 1,293 | $ 939 |
| Enhertu | ||||
| Disclosure of products and services [line items] | ||||
| Alliance revenue | 834 | 683 | ||
| Tezspire | ||||
| Disclosure of products and services [line items] | ||||
| Alliance revenue | 285 | 180 | ||
| Beyfortus | ||||
| Disclosure of products and services [line items] | ||||
| Alliance revenue | 109 | 26 | ||
| Datroway | ||||
| Disclosure of products and services [line items] | ||||
| Alliance revenue | 14 | |||
| Other Alliance Revenue | ||||
| Disclosure of products and services [line items] | ||||
| Alliance revenue | $ 51 | $ 50 | ||