Product Sales year-on-year analysis: H1 2025 |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | World | | US | | Emerging Markets | | Europe | | Established RoW | For the half year ended 30 June | | | | Change | | | | Change | | | | Change | | | | Change | | | | Change | | | $m | | Act % | | CER % | | $m | | Act % | | $m | | Act % | | CER % | | $m | | Act % | | CER % | | $m | | Act % | | CER % | Tagrisso | | 3,488 | | 9 | | 10 | | 1,439 | | 12 | | 1,008 | | 10 | | 13 | | 658 | | 5 | | 5 | | 383 | | 3 | | 3 | Imfinzi | | 2,716 | | 20 | | 21 | | 1,572 | | 31 | | 294 | | 20 | | 28 | | 537 | | 17 | | 17 | | 313 | | (11) | | (11) | Calquence | | 1,634 | | 8 | | 9 | | 1,090 | | 4 | | 103 | | 36 | | 49 | | 368 | | 15 | | 15 | | 73 | | 12 | | 15 | Lynparza | | 1,564 | | 8 | | 9 | | 689 | | 14 | | 323 | | 1 | | 4 | | 425 | | 7 | | 6 | | 127 | | 1 | | 2 | Enhertu | | 428 | | 72 | | 76 | | - | | - | | 292 | | 82 | | 88 | | 94 | | 65 | | 63 | | 42 | | 35 | | 41 | Zoladex | | 567 | | 3 | | 6 | | 9 | | 16 | | 442 | | 7 | | 10 | | 72 | | (7) | | (8) | | 44 | | (10) | | (9) | Truqap | | 302 | | n/m | | n/m | | 253 | | 80 | | 8 | | n/m | | n/m | | 28 | | n/m | | n/m | | 13 | | n/m | | n/m | Imjudo | | 170 | | 25 | | 25 | | 111 | | 26 | | 12 | | 58 | | 68 | | 23 | | 43 | | 43 | | 24 | | (1) | | (2) | Other Oncology | | 216 | | (10) | | (8) | | 4 | | (63) | | 146 | | (7) | | (5) | | 10 | | (16) | | (16) | | 56 | | (6) | | (7) | Oncology | | 11,085 | | 14 | | 15 | | 5,167 | | 18 | | 2,628 | | 14 | | 19 | | 2,215 | | 13 | | 12 | | 1,075 | | (1) | | - | Farxiga | | 4,206 | | 11 | | 13 | | 803 | | (7) | | 1,730 | | 17 | | 23 | | 1,448 | | 17 | | 17 | | 225 | | 7 | | 7 | Crestor | | 635 | | 8 | | 10 | | 24 | | 11 | | 547 | | 15 | | 17 | | - | | n/m | | n/m | | 64 | | (9) | | (8) | Brilinta | | 520 | | (22) | | (21) | | 271 | | (23) | | 137 | | (18) | | (16) | | 107 | | (21) | | (21) | | 5 | | (39) | | (34) | Seloken | | 308 | | (2) | | 2 | | - | | n/m | | 298 | | (3) | | 1 | | 8 | | 34 | | 38 | | 2 | | (9) | | (5) | Lokelma | | 328 | | 31 | | 32 | | 144 | | 25 | | 63 | | 50 | | 54 | | 56 | | 36 | | 36 | | 65 | | 27 | | 26 | roxadustat | | 150 | | (8) | | (7) | | - | | - | | 150 | | (8) | | (7) | | - | | - | | - | | - | | - | | - | Wainua | | 84 | | n/m | | n/m | | 82 | | n/m | | 1 | | - | | - | | 1 | | - | | - | | - | | - | | - | Other CVRM | | 274 | | (27) | | (26) | | 27 | | (74) | | 138 | | 14 | | 16 | | 76 | | (37) | | (37) | | 33 | | 7 | | 7 | CVRM | | 6,505 | | 6 | | 7 | | 1,351 | | (9) | | 3,064 | | 11 | | 15 | | 1,696 | | 9 | | 9 | | 394 | | 6 | | 6 | Symbicort | | 1,438 | | (4) | | (2) | | 598 | | - | | 400 | | (11) | | (8) | | 272 | | (5) | | (5) | | 168 | | 7 | | 10 | Fasenra | | 920 | | 18 | | 18 | | 556 | | 16 | | 52 | | 26 | | 32 | | 229 | | 19 | | 19 | | 83 | | 19 | | 20 | Breztri | | 583 | | 28 | | 29 | | 295 | | 31 | | 156 | | 19 | | 21 | | 87 | | 34 | | 34 | | 45 | | 34 | | 36 | Tezspire | | 198 | | 99 | | n/m | | - | | - | | 16 | | n/m | | n/m | | 128 | | n/m | | n/m | | 54 | | 61 | | 63 | Pulmicort | | 264 | | (30) | | (28) | | 4 | | (57) | | 208 | | (34) | | (32) | | 34 | | (8) | | (7) | | 18 | | 8 | | 11 | Saphnelo | | 304 | | 49 | | 49 | | 265 | | 44 | | 7 | | n/m | | n/m | | 21 | | n/m | | n/m | | 11 | | 45 | | 45 | Airsupra | | 70 | | n/m | | n/m | | 69 | | n/m | | 1 | | n/m | | n/m | | - | | - | | - | | - | | - | | - | Other R&I | | 158 | | (8) | | (8) | | 55 | | 4 | | 70 | | (18) | | (17) | | 29 | | (2) | | (3) | | 4 | | (4) | | - | R&I | | 3,935 | | 9 | | 10 | | 1,842 | | 18 | | 910 | | (12) | | (9) | | 800 | | 18 | | 17 | | 383 | | 19 | | 21 | Beyfortus | | 128 | | n/m | | n/m | | 102 | | 91 | | - | | - | | - | | 24 | | n/m | | n/m | | 2 | | n/m | | n/m | Synagis | | 162 | | (36) | | (33) | | (1) | | (22) | | 121 | | (8) | | (3) | | 25 | | (62) | | (60) | | 17 | | (70) | | (71) | FluMist | | 10 | | 20 | | 16 | | - | | n/m | | - | | n/m | | n/m | | - | | n/m | | n/m | | 10 | | n/m | | n/m | Other V&I | | 1 | | (91) | | (91) | | - | | - | | - | | n/m | | n/m | | 1 | | (91) | | (91) | | - | | n/m | | n/m | V&I | | 301 | | (7) | | (5) | | 101 | | 82 | | 121 | | (7) | | (3) | | 50 | | (39) | | 37 | | 29 | | (49) | | (50) | Ultomiris | | 2,228 | | 23 | | 24 | | 1,272 | | 23 | | 113 | | 71 | | 82 | | 498 | | 21 | | 21 | | 345 | | 17 | | 17 | Soliris | | 974 | | (32) | | (30) | | 568 | | (30) | | 224 | | (12) | | (1) | | 112 | | (57) | | (57) | | 70 | | (40) | | (38) | Strensiq | | 746 | | 14 | | 15 | | 584 | | 10 | | 50 | | 61 | | 67 | | 57 | | 19 | | 20 | | 55 | | 24 | | 23 | Koselugo | | 275 | | 11 | | 13 | | 106 | | 5 | | 76 | | (9) | | (5) | | 71 | | 58 | | 58 | | 22 | | 25 | | 25 | Other Rare Disease | | 113 | | 12 | | 14 | | 54 | | 16 | | 20 | | 4 | | 16 | | 34 | | 12 | | 12 | | 5 | | 9 | | 10 | Rare Disease | | 4,336 | | 2 | | 3 | | 2,584 | | 3 | | 483 | | 6 | | 16 | | 772 | | (3) | | (3) | | 497 | | 4 | | 4 | Nexium | | 426 | | (7) | | (5) | | 37 | | (21) | | 333 | | 5 | | 8 | | 17 | | (35) | | (35) | | 39 | | (43) | | (41) | Other | | 82 | | (19) | | (18) | | 3 | | (46) | | 59 | | (12) | | (11) | | 18 | | (32) | | (33) | | 2 | | 8 | | 7 | Other Medicines | | 508 | | (9) | | (7) | | 40 | | (23) | | 392 | | 2 | | 4 | | 35 | | (34) | | (34) | | 41 | | (41) | | (40) | Total Medicines | | 26,670 | | 8 | | 10 | | 11,085 | | 10 | | 7,598 | | 8 | | 12 | | 5,568 | | 8 | | 8 | | 2,419 | | 2 | | 2 |
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