v3.25.2
Condensed consolidated statement of comprehensive income - USD ($)
shares in Millions, $ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Condensed consolidated statement of comprehensive income        
Product Sales $ 13,795 $ 12,452 $ 26,670 $ 24,629
Alliance revenue 654 482 1,293 939
Product Revenue 14,449 12,934 27,963 25,568
Collaboration Revenue 8 4 82 49
Total Revenue 14,457 12,938 28,045 25,617
Cost of sales (2,473) (2,183) (4,714) (4,401)
Gross profit 11,984 10,755 23,331 21,216
Distribution expense (143) (132) (278) (267)
Research and development expense (3,548) (3,008) (6,707) (5,791)
Selling, general and administrative expense (4,864) (4,929) (9,356) (9,424)
Other operating income and expense 79 60 192 127
Operating profit 3,508 2,746 7,182 5,861
Finance income 68 100 149 211
Finance expense (439) (443) (785) (856)
Share of after tax losses in associates and joint ventures (10) (6) (17) (19)
Profit before tax 3,127 2,397 6,529 5,197
Taxation (679) (469) (1,160) (1,089)
Profit for the period 2,448 1,928 5,369 4,108
Other comprehensive income:        
Remeasurement of the defined benefit pension liability (81) (43) (30) 101
Net (losses)/gains on equity investments measured at fair value through other comprehensive income (67) 54 (125) 89
Fair value movements related to own credit risk on bonds designated as fair value through profit or loss   12   12
Tax on items that will not be reclassified to profit or loss 14 12 (3) (27)
Total other comprehensive income that will not be reclassified to profit or loss, net of tax (134) 35 (158) 175
Foreign exchange arising on consolidation 1,312 (39) 2,464 (554)
Foreign exchange arising on designated liabilities in net investment hedges (43) 2 10 (96)
Fair value movements on cash flow hedges 201 (52) 273 (138)
Fair value movements on cash flow hedges transferred to profit and loss (213) 32 (315) 102
Fair value movements on derivatives designated in net investment hedges (10) 23 (20) 45
Gains/(costs) of hedging 18 (1) 10 14
Tax on items that may be reclassified subsequently to profit or loss (22) 3 (52) 38
Total other comprehensive income that may be reclassified subsequently to profit or loss, net of tax 1,243 (32) 2,370 (589)
Other comprehensive income/(expense), net of tax 1,109 3 2,212 (414)
Total comprehensive income for the period 3,557 1,931 7,581 3,694
Profit attributable to:        
Owners of the Parent 2,450 1,927 5,366 4,106
Non-controlling interests (2) 1 3 2
Profit for the period 2,448 1,928 5,369 4,108
Total comprehensive income attributable to:        
Owners of the Parent 3,556 1,930 7,574 3,692
Non-controlling interests 1 1 7 2
Total comprehensive income for the period $ 3,557 $ 1,931 $ 7,581 $ 3,694
Earnings per share [abstract]        
Basic earnings per $0.25 Ordinary Share $ 1.58 $ 1.24 $ 3.46 $ 2.65
Diluted earnings per $0.25 Ordinary Share $ 1.57 $ 1.24 $ 3.44 $ 2.63
Diluted weighted average number of Ordinary Shares in issue (millions) 1,559 1,560 1,560 1,560
Weighted average number of Ordinary Shares in issue (millions) 1,550 1,550 1,550 1,549