Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in this Registration Statement on Form S-3 of Rapport Therapeutics, Inc. of our report dated March 11, 2025 relating to the financial statements, which appears in Rapport Therapeutics, Inc.s Annual Report on Form 10-K for the year ended December 31, 2024. We also consent to the reference to us under the heading Experts in such Registration Statement.
/s/ PricewaterhouseCoopers LLP
Boston, Massachusetts
July 1, 2025
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