Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in this Registration Statement on Form S-3 of ADC Therapeutics SA of our report dated March 27, 2025 relating to the financial statements, which appears in ADC Therapeutics SA‘s Annual Report on Form 10-K for the year ended December 31, 2024. We also consent to the reference to us under the heading "Experts "in such Registration Statement.

Lausanne, Switzerland
June 30, 2025 

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