F-3 F-3ASR EX-FILING FEES 0001395064 TAKEDA PHARMACEUTICAL CO LTD 0001395064 2025-06-24 2025-06-24 0001395064 1 2025-06-24 2025-06-24 0001395064 2 2025-06-24 2025-06-24 0001395064 3 2025-06-24 2025-06-24 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

F-3

TAKEDA PHARMACEUTICAL CO LTD

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Debt Senior Debt Securities of Takeda Pharmaceutical Company Limited 457(r) 0.0001531
Fees to be Paid 2 Debt Guaranteed Senior Debt Securities of Takeda U.S. Financing, Inc. 457(r) 0.0001531
Fees to be Paid 3 Other Guarantees of Takeda Pharmaceutical Company Limited in connection with Guaranteed Senior Debt Securities Other 0.0001531 $ 0.00
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 0.00

$ 0.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 0.00

Offering Note

1

(1a) An indeterminate aggregate initial offering price or number of securities are being registered and may from time to time be offered at indeterminate prices. (1b) In accordance with Rules 456(b) and 457(r) under the Securities Act, the Registrants are deferring payment of all of the registration fee.

2

See notes (1a) & (1b) above.

3

Pursuant to Rule 457(n), no separate fee for the guarantees is payable.