
	JPY (millions)
Acquisition cost	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Land		Construction in progress		Total
As of April 1, 2023	¥	1,400,108	¥	851,382	¥	141,867	¥	98,227	¥	207,400	¥	2,698,984
Additions and other increases	158,460		27,662		11,508		5		126,788		324,423

Transfers	26,434		39,784		10,803		—		(77,021)		—
Disposals and other decreases	(45,337)		(11,583)		(10,694)		(9)		(2,817)		(70,440)
Reclassification to assets held for sale (Note 19)	(9,188)		(6,236)		(483)		(597)		(53)		(16,558)

Foreign currency translation differences	148,576		80,936		11,946		8,220		24,391		274,069
As of March 31, 2024	¥	1,679,054	¥	981,944	¥	164,945	¥	105,845	¥	278,689	¥	3,210,478
Additions and other increases	37,969		22,271		10,480		—		154,435		225,155

Transfers	36,236		48,722		13,185		68		(98,211)		—
Disposals and other decreases	(36,322)		(29,931)		(5,668)		(0)		(7,325)		(79,245)
Reclassification to assets held for sale (Note 19)	(22,552)		(15,493)		(346)		(399)		(12)		(38,803)

Foreign currency translation differences	(22,509)		(12,205)		(2,539)		(1,172)		(5,920)		(44,345)
As of March 31, 2025	¥	1,671,876	¥	995,309	¥	180,056	¥	104,342	¥	321,656	¥	3,273,239


Accumulated depreciation and accumulated impairment losses
As of April 1, 2023	¥	(419,530)	¥	(486,618)	¥	(98,207)	¥	(243)	¥	(3,156)	¥	(1,007,755)
Depreciation expenses	(80,067)		(71,588)		(18,684)		—		—		(170,339)
Impairment losses	(1,082)		(4,039)		(781)		—		(9,552)		(15,454)
Disposals and other decreases	22,173		8,682		10,127		—		1,210		42,192
Reclassification to assets held for sale (Note 19)	7,961		5,353		419		—		—		13,733

Foreign currency translation differences	(36,879)		(37,869)		(8,058)		(30)		(242)		(83,078)
As of March 31, 2024	¥	(507,425)	¥	(586,080)	¥	(115,184)	¥	(273)	¥	(11,739)	¥	(1,220,701)
Depreciation expenses	(86,344)		(66,372)		(20,676)		—		—		(173,392)
Impairment losses	(498)		(830)		(116)		—		(3,333)		(4,778)
Disposals and other decreases	19,132		24,985		5,341		—		2,840		52,298
Reclassification to assets held for sale (Note 19)	14,087		11,642		192		47		—		25,968

Foreign currency translation differences	6,892		6,541		1,974		3		166		15,575
As of March 31, 2025	¥	(554,156)	¥	(610,114)	¥	(128,469)	¥	(223)	¥	(12,068)	¥	(1,305,030)


	JPY (millions)
Carrying amount	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Land		Construction in progress		Total
As of April 1, 2023	¥	980,578	¥	364,763	¥	43,660	¥	97,983	¥	204,245	¥	1,691,229
As of March 31, 2024	1,171,629		395,865		49,761		105,572		266,950		1,989,777
As of March 31, 2025	1,117,720		385,195		51,587		104,119		309,589		1,968,209


	JPY (millions)
Acquisition cost of ROU Assets	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Total
As of April 1, 2023	¥	573,585	¥	16,818	¥	320	¥	590,724
Additions and other increases	136,969		7,950		31		144,950
Disposals and other decreases	(36,468)		(4,840)		(33)		(41,341)
Reclassification to assets held for sale (Note 19)	(408)		(38)		(127)		(573)
Foreign currency translation differences	68,220		1,988		20		70,228
As of March 31, 2024	¥	741,898	¥	21,880	¥	211	¥	763,989
Additions and other increases	18,118		6,867		—		24,986
Disposals and other decreases	(32,499)		(4,677)		(110)		(37,286)

Foreign currency translation differences	(10,687)		(795)		(2)		(11,484)
As of March 31, 2025	¥	716,831	¥	23,275	¥	98	¥	740,204


	JPY (millions)
Accumulated depreciation and accumulated impairment losses of ROU Assets	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Total
As of April 1, 2023	¥	(172,149)	¥	(8,037)	¥	(264)	¥	(180,450)
Depreciation expenses	(45,635)		(5,286)		(33)		(50,954)

Disposals and other decreases	17,251		4,221		33		21,505
Reclassification to assets held for sale (Note 19)	405		38		120		562
Foreign currency translation differences	(20,368)		(865)		(16)		(21,249)
As of March 31, 2024	¥	(220,496)	¥	(9,930)	¥	(160)	¥	(230,586)
Depreciation expenses	(44,571)		(6,065)		(19)		(50,656)

Disposals and other decreases	14,587		3,741		109		18,437

Foreign currency translation differences	3,738		352		2		4,092
As of March 31, 2025	¥	(246,742)	¥	(11,902)	¥	(68)	¥	(258,712)


	JPY (millions)
Carrying amount of ROU Assets	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Total
As of April 1, 2023	¥	401,437	¥	8,781	¥	56	¥	410,274
As of March 31, 2024	521,403		11,950		51		533,403
As of March 31, 2025	470,089		11,373		30		481,492


	JPY (millions) For the Year Ended March 31
	2023		2024		2025
Expense relating to short-term leases	¥	4,521	¥	4,312	¥	4,160
Expense relating to leases of low-value assets that are not short-term leases expenses	1,255		887		493
Expense relating to variable lease payments	4,794		10,954		11,250
Total expenses not included in lease liabilities	¥	10,570	¥	16,152	¥	15,904
Total cash outflow for leases not included in lease liabilities	¥	10,570	¥	16,152	¥	15,904

The total cash outflow for leases on lease liabilities for the years ended March 31, 2023, 2024 and 2025 was JPY 59,981 million, JPY 75,412 million and JPY 69,685 million, respectively. Also, the total future cash outflow for leases not yet commenced to which Takeda is committed for the year ended March 31, 2025 is JPY 221,192 million.


	JPY (millions) For the Year Ended March 31
	2023		2024		2025
Cost of sales	¥	(375)	¥	(6,225)	¥	(1,485)
Selling, general and administrative expenses	(75)		—		(34)
Research and development expenses	—		(1,307)		(1)
Other operating expenses	(1,881)		(7,923)		(3,257)
Total	¥	(2,331)	¥	(15,454)	¥	(4,778)

Impairment losses for the year ended March 31, 2024 resulted primarily from production facilities, whose recoverable amounts were nil, related to ALOFISEL (for complex Crohn's perianal fistulas) following topline results of the phase 3 ADMIRE-CD Ⅱ trial.