v3.25.2
Document and Entity Information
Jun. 17, 2025
Cover [Abstract]  
Amendment Flag false
Entity Central Index Key 0001636282
Document Type 8-K
Document Period End Date Jun. 17, 2025
Entity Registrant Name SPYRE THERAPEUTICS, INC.
Entity Incorporation State Country Code DE
Entity File Number 001-37722
Entity Tax Identification Number 46-4312787
Entity Address, Address Line One 221 Crescent Street
Entity Address, Address Line Two Building 23
Entity Address, Address Line Three Suite 105
Entity Address, City or Town Waltham
Entity Address, State or Province MA
Entity Address, Postal Zip Code 02453
City Area Code 617
Local Phone Number 651-5940
Written Communications false
Soliciting Material false
Pre Commencement Tender Offer false
Pre Commencement Issuer Tender Offer false
Security 12b Title Common Stock, $0.0001 Par Value Per Share
Trading Symbol SYRE
Security Exchange Name NASDAQ
Entity Emerging Growth Company false