Exhibit 107

 

Calculation of Filing Fee Table

 

FORM S-1

(Form Type)

 

AYTU BIOPHARMA, INC.

(Exact Name of Registrant as Specified in its Charter)

 

Table 1: Newly Registered Securities

 

 

Security
Type

Security

Class

Title

Fee
Calculation

Amount
Registered

Proposed
Maximum
Offering
Price Per
Unit

Maximum
Aggregate
Offering

Price(1)

Fee

Rate

Amount of
Registration
Fee(2)

Fees to Be Paid

Equity

Common Stock, par value $0.0001 per share

457(o)

   

$2,760,000

0.00015310

$422.56

 

Other

Prefunded Warrants to purchase shares of Common Stock (3)

Other

   

-

   
 

Equity

Common Stock underlying the Prefunded Warrants(3)

457(o)

   

-

   
 

Total Offering Amounts

 

$2,760,000

0.00015310

$422.56

 

Total Fees Previously Paid

     

-

 

Total Fee Offsets

     

-

 

Net Fee Due

     

$422.56

 

(1)

Represents only the additional shares of the Registrant’s common stock, par value $0.0001 per share (“Common Stock”) being registered. Does not include the securities that the Registrant previously registered on the Registration Statement on Form S-1, as amended, (File No. 333-287728) (the “Prior Registration Statement”), which was declared effective by the United States Securities and Exchange Commission on June 5, 2025.

   

(2)

The Registrant previously registered an aggregate of $13,800,000 of its Common Stock on the Prior Registration Statement, for which the Registrant previously paid a filing fee of $2,112.78. In accordance with Rule 462(b) under the Securities Act of 1933, as amended, an additional amount of securities having the proposed maximum aggregate offering price of $2,760,000 is hereby registered, which includes shares issuable upon the exercise of the underwriters’ option to purchase additional shares.

   

(3)

The proposed maximum aggregate offering price of the shares of Common Stock will be reduced on a dollar-for-dollar basis based on the offering price of any prefunded warrants issued in the offering, and the proposed maximum aggregate offering price of the prefunded warrants to be issued in the offering will be reduced on a dollar-for-dollar basis based on the offering price of any shares of Common Stock issued in the offering.