v3.25.1
Commitments Under Research and Collaboration Agreements (Details) - USD ($)
$ in Thousands
 1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2025
Mar. 31, 2022
Mar. 31, 2025
Mar. 31, 2024
Dec. 31, 2024
Dec. 31, 2023
Commitments under Research and Collaboration Agreements [Line Items]            
Milestone payments     $ 11,100   $ 11,100  
Clinical development milestones.     14,000   14,000  
Regulatory events     80,000   80,000  
Commercial sales     $ 150,000   $ 150,000  
Net sales of licensed products milestone payment     $3,995   $3,995  
Milestone payments commercial milestones     $ 12,000   $ 12,000  
Extension royalties   $ 225     225  
Accrued extension royalties   $ 200     200 $ 200
Development milestones     32,500   32,500  
Annual sales milestone payments     $ 50,000   $ 50,000  
Net profits from licensed product sales     50.00%   50.00%  
Payment of development milestones     $ 3,300      
Accrued amount     3,300   $ 3,300  
Patent costs reimbursements         0 49
Accrued liabilities $ 325   325   325 379
Other income     $ 3,556 3,556
Research and Development Expense [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Milestone payments     70,000   70,000  
Royalties amount     6 $ 6 25 25
MedImmune License Agreement [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Milestone payments     244,000   244,000  
NCI License Agreement [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Royalties amount     25      
MSK License Agreement [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Milestone payment upon achieving     10,500   10,500  
Milestone payment on net sales     30,000   30,000  
Accrued royalties 790   790   790  
VAZYME License agreement [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Milestone payments     200   200  
Accrued liabilities 200   200   200 200
Other Accrued Expenses and Accounts Payable [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Patent costs reimbursements     273   273 273
Other Accrued Expenses [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Patent costs reimbursements     169   169 169
Accounts Payable [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Milestone payments           790
Subsequent Event [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Payment of development milestones $ 3,300          
Minimum [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Royalties amount     20   20  
Minimum [Member] | Research and Development Expense [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Royalties amount         0 $ 20
Minimum [Member] | NCI License Agreement [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Royalties amount         25  
Maximum [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Royalties amount     $ 30   30  
Maximum [Member] | Research and Development Expense [Member]            
Commitments under Research and Collaboration Agreements [Line Items]            
Royalties amount         $ 498,000