v3.25.1
Document And Entity Information
12 Months Ended
Jun. 30, 2025
Document Information [Line Items]  
Entity Central Index Key 0001385818
Entity Registrant Name AYTU BIOPHARMA, INC
Amendment Flag false
Document Fiscal Period Focus FY
Document Fiscal Year Focus 2025
Document Type S-1
Entity Incorporation, State or Country Code DE
Entity Tax Identification Number 47-0883144
Entity Address, Address Line One 7900 East Union Avenue, Suite 920
Entity Address, City or Town Denver
Entity Address, State or Province CO
Entity Address, Postal Zip Code 80237
City Area Code 720
Local Phone Number 437-6580
Entity Filer Category Non-accelerated Filer
Entity Small Business true
Entity Emerging Growth Company false