| Schedule of outstanding and exercisable options |
| | | | | | | | | | | | | | | | 2025 | | | | | | | | | | | | | Weighted | | | Number | | | | average | | | of shares | | | | exercise | | | 2019 Plan | | Inducement Plan | | 2011 Plan | | Total | | price | Outstanding at beginning of period - 2011 Plan | | | — | | — | | | 1,632,485 | | 1,632,485 | | $ | 2.11 | Outstanding at beginning of period - 2019 Plan | | | 7,604,606 | | — | | | — | | 7,604,606 | | | 4.97 | Outstanding at beginning of period - Inducement Plan | | | — | | 496,000 | | | — | | 496,000 | | | 5.99 | Granted - 2019 Plan | | | 1,151,400 | | — | | | — | | 1,151,400 | | | 2.02 | Granted - Inducement Plan | | | — | | 244,000 | | | — | | 244,000 | | | 2.01 | Outstanding at end of period | | | 8,756,006 | | 740,000 | | | 1,632,485 | | 11,128,491 | | $ | 4.22 | Outstanding at end of period - Weighted average exercise price | | $ | 4.58 | $ | 4.68 | | $ | 2.11 | | | | | | Exercisable at end of period | | | 5,795,146 | | 350,292 | | | 1,632,485 | | 7,777,923 | | $ | 4.85 | Exercisable at end of period - Weighted average exercise price | | $ | 5.54 | $ | 6.22 | | $ | 2.11 | | | | | |
| | | | | | | | | | | | | | | | 2024 | | | | | | | | | | | | | Weighted | | | Number | | | | average | | | of shares | | | | exercise | | | 2019 Plan | | Inducement Plan | | 2011 Plan | | Total | | price | Outstanding at beginning of period - 2011 Plan | | | — | | — | | | 1,694,233 | | 1,694,233 | | $ | 2.09 | Outstanding at beginning of period - 2019 Plan | | | 6,406,897 | | — | | | — | | 6,406,897 | | | 5.82 | Outstanding at beginning of period - Inducement Plan | | | — | | 625,000 | | | — | | 625,000 | | | 5.74 | Granted - 2019 Plan | | | 45,000 | | — | | | — | | 45,000 | | | 1.45 | Forfeited - Inducement Plan | | | — | | (98,250) | | | — | | (98,250) | | | 4.33 | Forfeited - 2019 Plan | | | (386,053) | | — | | | — | | (386,053) | | | 4.42 | Expired - 2019 Plan | | | (13,722) | | — | | | — | | (13,722) | | | 6.36 | Outstanding at end of period | | | 6,052,122 | | 526,750 | | | 1,694,233 | | 8,273,105 | | $ | 5.11 | Outstanding at end of period - Weighted average exercise price | | $ | 5.88 | $ | 6.00 | | $ | 2.09 | | | | | | Exercisable at end of period | | | 3,819,413 | | 250,271 | | | 1,694,233 | | 5,763,917 | | $ | 5.24 | Exercisable at end of period - Weighted average exercise price | | $ | 6.56 | | 6.42 | | $ | 2.09 | | | | | |
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| Schedule of non-vested share options activity |
| | | | | | | | | | | | | | | | | 2025 | | | Number | | | | Weighted | | | of options | | | | average | | | 2019 Plan | | Inducement Plan | | 2011 Plan | | Total | | fair value | Non-vested share options at beginning of period - 2019 Plan | | | 2,754,054 | | | — | | | — | | 2,754,054 | | | 2.33 | Non-vested share options at beginning of period - Inducement Plan | | | — | | | 176,709 | | | — | | 176,709 | | | 4.19 | Granted - 2019 Plan | | | 1,151,400 | | | — | | | — | | 1,151,400 | | | 1.64 | Granted - Inducement Plan | | | — | | | 244,000 | | | — | | 244,000 | | | 1.60 | Vested, outstanding - 2019 Plan | | | (944,594) | | | — | | | — | | (944,594) | | | 2.12 | Vested, outstanding - Inducement Plan | | | — | | | (31,001) | | | — | | (31,001) | | | 4.53 | Non-vested share options at end of period | | | 2,960,860 | | | 389,708 | | | — | | 3,350,568 | | $ | 2.18 | Non-vested share options at end of period - Weighted average fair value | | $ | 2.13 | | $ | 2.54 | | $ | — | | | | | |
| | | | | | | | | | | | | | | | | 2024 | | | Number | | | | Weighted | | | of options | | | | average | | | 2019 Plan | | Inducement Plan | | 2011 Plan | | Total | | fair value | Non-vested share options at beginning of period - 2019 Plan | | | 3,178,475 | | | — | | | — | | 3,178,475 | | | 3.64 | Non-vested share options at beginning of period - Inducement Plan | | | — | | | 403,167 | | | — | | 403,167 | | | 4.07 | Granted - 2019 Plan | | | 45,000 | | | — | | | — | | 45,000 | | | 1.12 | Vested, outstanding - 2019 Plan | | | (604,713) | | | — | | | — | | (604,713) | | | 3.54 | Vested, outstanding - Inducement Plan | | | — | | | (28,438) | | | — | | (28,438) | | | 4.85 | Forfeited - Inducement Plan | | | — | | | (98,250) | | | — | | (98,250) | | | 3.31 | Forfeited - 2019 Plan | | | (386,053) | | | — | | | — | | (386,053) | | | 3.47 | Non-vested share options at end of period | | | 2,232,709 | | | 276,479 | | | — | | 2,509,188.00 | | $ | 3.71 | Non-vested share options at end of period - Weighted average fair value | | $ | 3.64 | | $ | — | | $ | — | | | | | |
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