Collaboration and License Agreements - Children's Medical Center Corporation (Details) - Children Medical Center Corporation $ in Millions	1 Months Ended
Apr. 30, 2018 USD ($) shares
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaboration and License Agreements
Shares issued (in shares) \| shares	15,123
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| Upon achievement of first licensed target
Collaboration and License Agreements
Maximum development milestone payable	$ 7.7
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| Upon achievement of second licensed target
Collaboration and License Agreements
Maximum development milestone payable	3.9
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement \| Upon achievement of third licensed target
Collaboration and License Agreements
Maximum development milestone payable	$ 1.9
Fulcrum Agreement
Collaboration and License Agreements
Percentage of upfront payment required upon first investigational new drug study	10.00%

Number of new stock issued during the period.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-SubTopic 10
-Topic 505
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481112/505-10-50-2

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(28))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(29))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Topic 946
-SubTopic 505
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478448/946-505-50-2

Reference 5: http://www.xbrl.org/2003/role/disclosureRef
-Topic 946
-SubTopic 220
-Name Accounting Standards Codification
-Section S99
-Paragraph 3
-Subparagraph (SX 210.6-09(4)(b))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479134/946-220-S99-3

Reference 6: http://www.xbrl.org/2003/role/disclosureRef
-Topic 946
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 3
-Subparagraph (SX 210.6-03(i)(1))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3

Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.3-04)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480008/505-10-S99-1

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Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration