v3.25.1
Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (52,195) $ (60,667)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 6,024 9,155
Depreciation and amortization expense 3,441 5,024
Net amortization and accretion on marketable securities (1,725) (4,367)
Loss on property and equipment disposals, net 1,291 15
Change in fair value of contingent consideration payable (1,211) 0
Non-cash lease income (710) (373)
Change in fair value of success payment liabilities (125) 968
Loss (gain) on marketable equity security 26 (1,535)
Impairment of other investments 0 13,001
Changes in operating assets and liabilities:    
Prepaid expenses, other current assets and other assets 2,000 595
Accounts payable (1,654) (113)
Accrued liabilities and other current liabilities (9,788) (3,606)
Other non-current liabilities (112) (113)
Net cash used in operating activities (54,738) (42,016)
CASH FLOWS FROM INVESTING ACTIVITIES    
Purchases of property and equipment (246) (30)
Purchases of marketable securities (84,411) (108,011)
Maturities of marketable securities 154,123 130,035
Net cash provided by investing activities 69,466 21,994
CASH FLOWS FROM FINANCING ACTIVITIES    
Proceeds from exercise of stock options 0 103
Taxes paid related to net share settlement of equity awards 1 (76)
Net cash provided by financing activities 1 27
Net increase (decrease) in cash, cash equivalents and restricted cash 14,729 (19,995)
Cash, cash equivalents and restricted cash at beginning of period 107,287 145,931
Cash, cash equivalents and restricted cash at end of period 122,016 125,936
Represented by:    
Cash and cash equivalents 120,328 125,650
Restricted cash 1,688 286
Total 122,016 125,936
SUPPLEMENTAL CASH FLOW INFORMATION    
Cash paid for amounts included in the measurement of lease liabilities 3,095 2,659
Non-cash investing and financing activities:    
Purchases of property and equipment included in accounts payable and accrued liabilities $ 155 $ 220